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ProteomicsIntegrative proteome and acetylome analyses of murine responses to Cryptococcus neoformans infection
Cryptococcus neoformans, an environmental opportunistic human fungal pathogen, is a causative agent for acute pulmonary infection and meningoencephalitis. Understanding the host’s response to C. neoformans infection is critical for developing effective treatment. Even though some have elucidated the...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-21 | PXD016614 | Pride
Lysine acetylome Mouse lung Cryptococcus neoformans infection Mouse brain 
MetabolomicsChanges and correlations of intestinal flora and liver metabolite profiles in mice with gallstones

There is increased appreciation for the roles of the gut-liver axis in liver and gall diseases. Specific gut microbes are associated with susceptibility to gallstone diseases,while the relationship between intestinal flora and liver metabolism in the formation of gallstones remains unclear. C57BL...

2021-08-05 | MTBLS2945 | MetaboLights
UnknownExploring the telehealth readiness and its related factors among palliative care specialist nurses: a cross-sectional study in China.
Not available
S-EPMC10303327 | biostudies-literature
MetabolomicsThe gut microbiota-butyrate axis restores cardiomyocyte autophagy to alleviate Doxorubicin-induced cardiotoxicity

Abstract

Background Doxorubicin (DOX), an anthracycline chemotherapeutic agent, is widely used for treating various malignancies. However, its clinical application is limited by dose-dependent cardiotoxicity (DOX-induced cardiotoxicity, DIC). Recent studies have shown that the gut microbiot...

2025-09-16 | MTBLS12997 | MetaboLights
UnknownNeutrophil/monocyte-targeted dual-ligands modified liposomes delivering puerarin for ischemia stroke treatment.
Not available
S-EPMC12281153 | biostudies-literature
UnknownRole of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease.
Not available
S-EPMC10726594 | biostudies-literature
ProteomicsProteomics of Esophageal Squamous Cell Carcinoma Response to anti-PD1 Immunotherapy Response
Immunotherapy has revolutionized cancer treatment, yet many patients do not respond. Here, we profile the proteome and phosphoproteome of clinical pre-treatment samples from 73 esophageal squamous cell carcinoma (ESCC) patients undergoing anti-programmed death 1 (PD1) immunotherapy.
ORGANISM(S): Homo Sapiens 
2026-03-31 | PXD076423 |
ProteomicsCheA pupylation sites identified by SPIDER assay
We used CheAs and biotin-CheZ to validate the efficiency of SPIDER capturing protein-protein interaction. Pupylation sites on WT CheAs after SPIDER assay was identified by LC-MS/MS analysis, by searching for an additional mass of ~243 Da, which represents the three C-terminal residues of Pup, i. e.,...
ORGANISM(S): Escherichia Coli 
2021-06-04 | PXD026509 |
ProteomicsPupylation sites on protein Sox2
As a test for the effectiveness of SPIDER with RNA-protein pairs, We used Sox2 and specific biotin-DNA and biotin-RNA to validate the efficiency of SPIDER capturing protein-nucleic acid interaction. Pupylation sites on Sox2 after SPIDER assay was identified by LC-MS/MS analysis, by searching for an ...
ORGANISM(S): Homo Sapiens 
2021-06-04 | PXD026517 |
ProteomicsA proteomic landscape of macrophage in mouse tissues
Macrophages, locating in essentially all tissues, are critical for innate immune responses and involved in the tissue homeostasis. Distinct macrophages populations in different tissues exhibited diverse gene expressions and biological processes. Previous studies have accessed the molecular signature...
ORGANISM(S): Mus Musculus 
2022-10-28 | PXD021583 |
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