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TranscriptomicsGlobal gene profiling comparison between hydrogen sulfide- and N-methyl-D-aspartate-induced neuronal deaths
Hydrogen sulfide (H2S), present in abundance in the mammalian brain, has recently been demonstrated to induce a dose- and time-dependent apoptotic-necrotic continuum in murine primary cortical neurons, which was successfully attenuated upon application of N-methyl-D-aspartate (NMDA) receptor antagon...
ORGANISM(S): Mus musculus 
2013-01-23 | E-GEOD-16035 | biostudies-arrayexpress
TranscriptomicsExpression data from Arabidopsis thaliana under dark and far-red light
FAR-RED ELONGATED HYPOCOTYL 3 (FHY3) and its homolog FAR-RED IMPAIRED RESPONSE 1 (FAR1) are two transposase-derived transcription factors initially identified as the key components in phytochrome A signaling and recently shown to function in the circadian clock. However, whether FHY3 and FAR1 are in...
ORGANISM(S): Arabidopsis thaliana 
2011-08-01 | E-GEOD-30712 | biostudies-arrayexpress
GenomicsChIP-Seq data from Arabidopsis thaliana under dark and far-red light
FAR-RED ELONGATED HYPOCOTYL 3 (FHY3) and its homolog FAR-RED IMPAIRED RESPONSE 1 (FAR1) are two transposase-derived transcription factors initially identified as the key components in phytochrome A signaling and recently shown to function in the circadian clock. However, whether FHY3 and FAR1 are in...
ORGANISM(S): Arabidopsis thaliana 
2011-08-02 | E-GEOD-30711 | biostudies-arrayexpress
TranscriptomicsGene expression profiling for early rice stamen
Plant organ formation, or organogenesis is the process in which the primordium derived from shoot apical meristem develops into an organ with a given shape and proper function, through a series of cell division and differentiation. To decipher the genetic program underling plant organ formation, we ...
ORGANISM(S): Oryza sativa Japonica Group 
2013-12-17 | E-GEOD-53347 | biostudies-arrayexpress
TranscriptomicsGlobal identification and characterization of intermediate-size non-coding RNAs in Oryza sativa
In this study, we employed a special size fractionation and cDNA library construction method followed by 454 deep sequencing to systematically profile rice intermediate-size ncRNAs. Our analysis resulted in the identification of 1349 ncRNAs in total, including 754 novel ncRNAs of an unknown function...
ORGANISM(S): Oryza sativa Japonica Group 
2012-07-27 | E-GEOD-39695 | biostudies-arrayexpress
ProteomicsChicken liver TMT-based proteomics
In order to investigate the chicken SLCO1B3 gene functin on the liver metabolism, we used the Yimeng blue eggshell and brown eggshell chickens as the chicken liver SLCO1B3 gene knock-down animal to do the proteomic analysis.
ORGANISM(S): Gallus gallus (Chicken) 
2021-09-09 | PXD022768 | Pride
Chicken Liver Proteome 
TranscriptomicsGenomic features and regulatory roles of intermediate-size non-coding RNAs in Arabidopsis
Recent advances in genome-wide techniques allowed the identification of thousands of non-coding RNAs with various sizes in eukaryotes, some of which have further been shown to serve important functions in many biological processes. However, in model plant Arabidopsis, novel intermediate-sized ncRNAs...
ORGANISM(S): Arabidopsis thaliana 
2014-01-20 | E-GEOD-44235 | biostudies-arrayexpress
ProteomicsSerum proteomics and metabolomics reveal the characteristics of the A1762T/G1764A mutations in conjunction with the G1896A mutation.
Background and Objective: CHB is a complex heterogeneous disease with a high incidence and mortality rate. Especially, the mutant strains with A1762T/G1764A and G1896A mutations gradually gained survival advantages during the population evolution process. However, our current understanding of the po...
ORGANISM(S): Homo sapiens (Human) 
2026-04-14 | PXD066939 | Pride
Proteomics Gene mutation Non-targeted metabolomics Genomics analysis Chb 
ProteomicsDown-regulation of Rab 5C-dependent Endocytosis and Glycolysis in Cisplatin-resistant Ovarian Cancer Cell Lines
Drug resistance poses a major challenge to ovarian cancer treatment. Understanding mechanisms of drug resistance is important for finding new therapeutic targets. In the present work, a cisplatin-resistant ovarian cancer cell line A2780-DR was established with a resistance index of 6.64. The cellula...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080724 | MassIVE
TranscriptomicsGene expression of genetically related and unrelated human embryonic stem cell lines
Gene expression of sibling human ES cell lines are more similar to each other than unrelated cell lines. Undifferentiated human embryonic stem cells were used for analysis. We sought to determine whether genetic differences underly variations between different human ES cell lines. Sibling cell lines...
ORGANISM(S): Homo sapiens 
2009-03-19 | E-GEOD-15294 | biostudies-arrayexpress
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