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ProteomicsProteomic profiling reveals the impact of surface functionalization on the protein corona formed on superparamagnetic iron oxide nanoparticles
The protein corona formed on the surface of nanomaterials is critical to understanding their biological behavior, as it is regulated by both the physicochemical properties of the nanomaterials and the physiological environment. The interplay between material synthesis characteristics, protein corona...
ORGANISM(S): Homo Sapiens 
PXD056769 |
UnknownAnti-angiogenic effect of a humanized antibody blocking the Wnt/β-catenin signaling pathway.
Not available
S-EPMC6636822 | biostudies-literature
ProteomicsPostgraduate Scientific Research Innovation Plan of Bengbu Medical College
Meropenem is one of the main antibiotics used in the clinical treatment of CRKP. This study demonstrated that some important metabolic changes occurred in Meropenem-induced CRKP-OMVs, The OMVs proteome expression profile indicates increased secretion of stress proteins released from Meropenem-induce...
ORGANISM(S): Klebsiella Pneumoniae Subsp. Pneumoniae Hs11286 
2023-12-05 | PXD047553 |
ProteomicsIdentification of key elements and pathways regulated by Yiqi Sanjie formula against colorectal cancer based on integrative analyses
The Yiqi Sanjie (YQSJ) formula has been proved to be clinically useful for stage III colorectal cancer (CRC) patients. However, the exact anti-tumor mechanisms of YQSJ and its main active component peiminine remain incompletely understood. This study aimed to comprehensively explore the characteriza...
ORGANISM(S): Homo Sapiens 
PXD037110 |
ProteomicsProteomic analysis of proteins interacting with MacroD1 in the mouse heart
Sepsis-Induced Myocardial Injury (SIMI) is a severe form of cardiac dysfunction that involves multiple mechanisms, including inflammatory damage and mitochondrial injury . Our research has demonstrated that MacroD1 plays a significant role in SIMI. By employing liquid chromatography-mass spectrometr...
ORGANISM(S): Mus <genus> 
2024-12-19 | PXD059021 |
ProteomicsMolecular characterization of advanced colorectal cancer using serum proteomics and metabolomics
To comprehensively reveal molecular characterization of advanced CRC, we applied integrated proteomic and metabolomic analyses on serum samples from 20 patients with CRC at stage III or IV. Methods In the present study, we took advantage of nanoscale liquid chromatography and quadrupole time-of-flig...
ORGANISM(S): Homo Sapiens 
PXD025041 |
ProteomicsAK2 promotes the migration and invasion of lung adenocarcinoma by activating TGF-β/Smad pathway in vitro and in vivo
Adenylate kinase 2 (AK2) is a wide-spread and highly conserved protein kinase whose main function is to catalyze the exchange of nucleotide phosphate groups. In this study, we showed that AK2 regulated tumor cell metastasis in lung adenocarcinoma. Positive expression of AK2 is related to lung adenoc...
ORGANISM(S): Homo Sapiens 
PXD028231 |
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