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ProteomicsProteomic profiling reveals the impact of surface functionalization on the protein corona formed on superparamagnetic iron oxide nanoparticles
The protein corona formed on the surface of nanomaterials is critical to understanding their biological behavior, as it is regulated by both the physicochemical properties of the nanomaterials and the physiological environment. The interplay between material synthesis characteristics, protein corona...
ORGANISM(S): Homo Sapiens 
2024-10-14 | PXD056769 |
UnknownAnti-angiogenic effect of a humanized antibody blocking the Wnt/β-catenin signaling pathway.
Not available
S-EPMC6636822 | biostudies-literature
ProteomicsAK2 promotes the migration and invasion of lung adenocarcinoma by activating TGF-β/Smad pathway in vitro and in vivo
Adenylate kinase 2 (AK2) is a wide-spread and highly conserved protein kinase whose main function is to catalyze the exchange of nucleotide phosphate groups. In this study, we showed that AK2 regulated tumor cell metastasis in lung adenocarcinoma. Positive expression of AK2 is related to lung adenoc...
ORGANISM(S): Homo sapiens (Human) 
2021-09-18 | PXD028247 | Pride
Lung adenocarcinoma Emt Tgf-β Tumor metastasis Ak2 
ProteomicsIdentification of key elements and pathways regulated by Yiqi Sanjie formula against colorectal cancer based on integrative analyses
The Yiqi Sanjie (YQSJ) formula has been proved to be clinically useful for stage III colorectal cancer (CRC) patients. However, the exact anti-tumor mechanisms of YQSJ and its main active component peiminine remain incompletely understood. This study aimed to comprehensively explore the characteriza...
ORGANISM(S): Homo Sapiens 
2022-09-30 | PXD037110 |
ProteomicsProteomic analysis of proteins interacting with MacroD1 in the mouse heart
Sepsis-Induced Myocardial Injury (SIMI) is a severe form of cardiac dysfunction that involves multiple mechanisms, including inflammatory damage and mitochondrial injury . Our research has demonstrated that MacroD1 plays a significant role in SIMI. By employing liquid chromatography-mass spectrometr...
ORGANISM(S): Mus <genus> 
2024-12-19 | PXD059021 |
ProteomicsMolecular characterization of advanced colorectal cancer using serum proteomics and metabolomics
To comprehensively reveal molecular characterization of advanced CRC, we applied integrated proteomic and metabolomic analyses on serum samples from 20 patients with CRC at stage III or IV. Methods In the present study, we took advantage of nanoscale liquid chromatography and quadrupole time-of-flig...
ORGANISM(S): Homo Sapiens 
2021-03-29 | PXD025041 |
ProteomicsMass spectrometry data for proteomics and PTM proteomics
Mass spectrometry data for proteomics and PTM proteomics
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-01-11 | PXD059701 |
ProteomicsAK2 promotes the migration and invasion of lung adenocarcinoma by activating TGF-β/Smad pathway in vitro and in vivo
Adenylate kinase 2 (AK2) is a wide-spread and highly conserved protein kinase whose main function is to catalyze the exchange of nucleotide phosphate groups. In this study, we showed that AK2 regulated tumor cell metastasis in lung adenocarcinoma. Positive expression of AK2 is related to lung adenoc...
ORGANISM(S): Homo Sapiens 
2021-09-09 | PXD028231 |
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