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Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
In this study, through naïve nanobody phage library screening, we have identified multiple nanobodies against human YAP with high affinity and specificity. The YAP nanobody was then fused to the RING domain of RNF4, creating a bio-Proteolysis-Targeting Chimera (bioPROTAC) molecule capable of selecti...
ORGANISM(S): Homo sapiens (Human) 
2025-11-03 | PXD063726 | Pride
Rho-associated kinase (ROCK) and zipper-interacting protein kinase (ZIPK) have been implicated in diverse physiological functions, including smooth muscle contraction, cell proliferation, cell adhesion, apoptosis, cell migration and inflammation. Many aspects of regulation via ROCK and ZIPK, however...
ORGANISM(S): Homo sapiens 
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