A total of 12 boys diagnosed with ASD were enrolled. The control group of TD boys included 8 age-matched individuals attending the Department of Child Healthcare for routine health checks during the same period.
The purpose of this project is to identify proteins that interact with EZH2 in the myeloma cell line RPMI8226, which will further allow us to analyze the downstream molecular mechanisms associated with EZH2.
From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...
SIRT3 is a NAD+-dependent mitochondrial protein deacetylase participating in the regulation of central metabolism and mitochondrial proteostasis. SIRT3 is downregulated in clear cell renal cell carcinoma (ccRCC), a main type of renal cancers, but the function of SIRT3 in tumorigenesis and developmen...
Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...
