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TranscriptomicsTranscriptome analyses using the Chen Lab Cotton 25k oligo microarray
The chip of cotton oligonucleotide microarrrays, which contain ~23,000 UniGenes from our own ESTs sequence project (Gossypium hirsutum L. TM-1 immature ovules (GH_TMO) ) and open resources, was developed. Transcriptome analyses were performed to compare gene expression changes in laser capture micro...
ORGANISM(S): Gossypium hirsutum 
2011-05-06 | E-GEOD-27506 | biostudies-arrayexpress
UnknownRandomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma.
Not available
S-EPMC6075852 | biostudies-literature
UnknownPublic Perceptions of Physician Attire and Professionalism in the US.
Not available
S-EPMC8325071 | biostudies-literature
UnknownGap junction regulation by calmodulin.
Not available
S-EPMC3989380 | biostudies-literature
ProteomicsCharacterization of Argonaute-containing protein complexes in Leishmania-infected human macrophages
Leishmania donovani, an intracellular protozoan parasite, is the causative agent of visceral leishmaniasis or kala-azar, the most severe form of leishmaniasis in humans. To date, our understanding of the molecular mechanisms associated with the pathogenicity of Leishmania infection is still limited....
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037042 | Pride
Leishmania Rnai Macrophage Lcmsms 
UnknownThe Impact of Payment Reform on Pediatric Craniofacial Fracture Care in Maryland.
Not available
S-EPMC8543597 | biostudies-literature
ProteomicsComprehensive proteomic analysis of autophagosomes derived from Leishmania infected macrophages
Autophagy has been implicated as a host defense mechanism against intracellular pathogens. However, certain intracellular pathogens such as Leishmania can manipulate the host’s autophagy to promote their survival. Recently, our findings regarding the regulation of autophagy by Leishmania donovani in...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD037057 | Pride
Parasitic infection Autophagy Autophagosome Leishmania donovani Host-pathogen interactions Lcmsms 
ProteomicsDefining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus
Enteric bacterial pathogens pose significant threats to human health; however, the mechanisms by which they infect the mammalian gut in the face of daunting host defenses remain to be fully defined. For the attaching and effacing (A/E) bacterial family member and murine pathogen Citrobacter rodentiu...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-17 | PXD061145 | Pride
Espc Mucus Air-liquid interface Colonoids Enteric pathogens 
ProteomicsLeishmania regulates host YY1: comparative proteomic analysis identifies infection modulated YY1 dependent proteinsLeishmania regulates host YY1: comparative proteomic analysis identifies infection modulated YY1 dependent proteins
The protein Yin-Yang 1 (YY1) is a ubiquitous multifunctional transcription factor. Interestingly, there are several cellular functions controlled by YY1 that could play a role in Leishmania pathogenesis. Leishmaniasis is a human disease caused by protozoan parasites of the genus Leishmania. This stu...
ORGANISM(S): Homo sapiens (Human) 
2025-03-14 | PXD059968 | Pride
Parasitic infection Leishmania Transcription factor Proteomics Host-pathogen interactions Lcmsms 
ProteomicsMultimodal cell maps as a foundation for structural and functional genomics
Human cells contain a complex hierarchy of components, many of which remain uncharted. Here we broadly identify subcellular components across the 10–9–10–5 meter range, via self-supervised fusion of immunofluorescence images and biophysical interactions measured for >5100 proteins in U2-OS human cel...
ORGANISM(S): Homo sapiens (Human) 
2025-01-08 | PXD052362 | Pride
Size-exclusion chromatography Protein-correlation profiling Lcmsms 
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