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UnknownAccelerated methotrexate, vinblastine, doxorubicin, and cisplatin is safe, effective, and efficient neoadjuvant treatment for muscle-invasive bladder cancer: results of a multicenter phase II study with molecular correlates of response and toxicity.
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S-EPMC4050203 | biostudies-literature
MetabolomicsMetabolomics reveals molecular signatures for psoriasis biomarkers and drug targets discovery
Psoriasis is a chronic skin disease that affects multiple systems and can be influenced by immunological, environmental, and genetic factors. The discovery of plasma biomarkers of psoriasis and the regulation of metabolic pathways helps us understand psoriasis and may assist clinicians in the diagno...
2024-09-26 | MTBLS5185 | MetaboLights
ProteomicsProteomics analysis for liver from WT and Hsd17b6 liver specific knockout mice
Eight weeks old LSL-Cas9 mice were injected with AAV2/8 expressing Cre driving by TBG promoter and sgRNA of gene of interest to specifically knockout gene in liver. In the present study, either control or sgHsd17b6 virus are injected. The mice are subjected to high fat choline dificient diet feeding...
ORGANISM(S): Mus Musculus 
2024-10-02 | PXD056581 |
ProteomicsProteomic analysis of extracellular vesicles from inflammatory fibroblasts in colorectal cancer lung metastasis
Pulmonary metastasis is a major cause of mortality in colorectal cancer (CRC), and the tumor microenvironment plays a critical role in metastatic progression. In particular, inflammatory fibroblasts have been implicated in shaping the metastatic niche; however, the molecular characteristics of their...
ORGANISM(S): Homo Sapiens 
2026-03-20 | PXD075933 |
TranscriptomicsSingle-cell RNAseq of Human T lymphocyte derived from H7N9 infected patients
Comparing transcriptomes of CD8 T cells derived from a fatal H7N9 influenza infection with those derived from a patient that survived the infection. Specifically, CD38+ HLA-DR+ cells were sorted by flow cytometry at different sampling time-points, and the transcriptome was analysed using Smart-seq2.
ORGANISM(S): Homo sapiens 
2018-01-30 | E-MTAB-6379 | biostudies-arrayexpress
ProteomicsComprehensive mass spectral libraries of human thyroid tissue and cells
We established deep-coverage thyroid-specific spectral libraries encompassing over 12,000 proteins, including samples from nine types of thyroid primary and lymph node metastases tissues and fifty thyroid cancer cell lines.
ORGANISM(S): Homo Sapiens 
2024-09-27 | PXD051051 |
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