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MetabolomicsThe lipid-metabolism enzyme ECI2 reduces neutrophil extracellular traps formation for colorectal cancer suppression
Abnormalities in ether lipid metabolism as well as the formation of neutrophil extracellular traps have recently been recognized as detrimental factors affecting tumorigenesis and progression. However, the role of abnormal ether lipid metabolism in colorectal cancer (CRC) evolution has not been repo...
2024-10-01 | MTBLS10323 | MetaboLights
UnknownPrevalence of sarcopenia in Chinese community-dwelling elderly: a systematic review.
Not available
S-EPMC9454186 | biostudies-literature
UnknownAnalysis of the significance and gender differences in the factors influencing antisocial behaviors among adolescents.
Not available
S-EPMC12037769 | biostudies-literature
UnknownLongitudinal impact of different categories of adverse childhood experiences on social participation and informal social support among middle-aged and older adults in China.
Not available
S-EPMC11980108 | biostudies-literature
UnknownThe classification, origin, and evolutionary dynamics of severe fever with thrombocytopenia syndrome virus circulating in East Asia.
Not available
S-EPMC11416872 | biostudies-literature
UnknownAssociations of the cardiometabolic index with insulin resistance, prediabetes, and diabetes in U.S. adults: a cross-sectional study.
Not available
S-EPMC11475834 | biostudies-literature
ProteomicsNuclear PTEN safeguards pre-mRNA splicing to link Golgi apparatus for its tumor suppressive role
Dysregulation of pre-mRNA alternative splicing (AS) is closely associated with cancers. However, the relationships between the AS and classic oncogenes/tumor suppressors are largely unknown. Here we show that the deletion of tumor suppressor PTEN alters pre-mRNA splicing in its phosphatase-independe...
ORGANISM(S): Homo sapiens (Human) 
2018-10-18 | PXD009681 | Pride
U2af2 Golgi Tumor suppressor Spliceosome Pten Golga2 Protein-protein interaction Alternative splicing 
UnknownRandomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.
Not available
S-EPMC6085179 | biostudies-literature
UnknownCDCP1 allosterically regulates the AMPK α1 subunit to enhance fatty acid oxidation in osteoblasts.
Not available
S-EPMC12817758 | biostudies-literature
ProteomicsGenome-scale CRISPRi screen identifies pcnB repression conferring overproduction of free fatty acids in Escherichia coli
In this study, we carried out genome-scale CRISPRi modulation combining fluorescence-activated cell sorting (FACS) and next-generation sequencing (NGS) to identify genetic determinants for FFAs overproduction in Escherichia coli. The pcnBi (AP) strain that repressed the expression of pcnB produced 2...
ORGANISM(S): Escherichia Coli 
2024-05-18 | PXD052390 |
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