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MetabolomicsGlobal Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress
“Dry eye” is a multi-factorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have been directed towards biomarker discovery for diagnosis, response to treatment and disease mechanisms...
2015-08-31 | MTBLS214 | MetaboLights
ProteomicsGlobal Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress
“Dry eye” is a multi-factorial inflammatory disease affecting the ocular surface. Tear hyperosmolarity in dry eye contributes to inflammation and cell damage. Recent research efforts on dry eye have been directed towards biomarker discovery for diagnosis, response to treatment and disease mechanisms...
ORGANISM(S): Homo sapiens (Human) 
2015-08-17 | PXD002661 | Pride
Metabonomics Proteomics Osmostic stress Metabolomics Swath Dry eye Hyperosmolarity Osmoprotectants Itraq 
MetabolomicsCustomized Consensus Spectral Library Building for Untargeted Quantitative Metabolomics Analysis with Data Independent Acquisition Mass Spectrometry and MetaboDIA Workflow
Data independent acquisition-mass spectrometry (DIA-MS) coupled with liquid chromatography is a promising approach for rapid, automatic sampling of MS/MS data in untargeted metabolomics. However, wide isolation windows in DIA-MS generate MS/MS spectra containing a mixed population of fragment ions t...
2018-03-26 | MTBLS417 | MetaboLights
ProteomicsDIA proteomic of serum samples for the exploration of the pathological mechanism of Obstetric Antiphospholipid syndorme
Obstetric Antiphospholipid syndrome (OAPS) is a multisystem disorder characterized by thrombosis and/or recurrent fetal loss. In this study, we aim to further explore the pathological mechanism of OAPS. Herein, we carried out quantitative proteomic analysis of serum samples from OAPS patients and he...
ORGANISM(S): Homo Sapiens 
2023-09-25 | PXD045626 |
ProteomicsA Diecast Mineralization Process Forms the Tough Mantis Shrimp Dactyl Club
Biomineralization, the process by which mineralized tissues grow and harden via biogenic mineral deposition, is a relatively lengthy process in many mineral-producing organisms,resulting in challenges to study the growth and biomineralization of complex hard mineralized tissues. ...
ORGANISM(S): Cellular Organisms 
2019-03-20 | PXD013153 | JPOST Repository
ProteomicsDeep proteomic analysis of circulating large/small extracellular vesicle enriched fraction based on data-independent acquisition mass spectrometry
Proteins in the plasma/serum mirror an individual’s physiology. Circulating extracellular vesicle (EVs) proteins constitute a large portion of the plasma/serum proteome. Thus, deep and unbiased proteomic analysis of circulating plasma/serum extracellular vesicles holds promise for discovering diseas...
ORGANISM(S): Homo Sapiens 
2023-06-26 | PXD043290 |
UnknownFTACMT study protocol: a multicentre, double-blind, randomised, placebo-controlled trial of faecal microbiota transplantation for autism spectrum disorder.
Not available
S-EPMC8804636 | biostudies-literature
ProteomicsStudy the effect of licorice-yuanhua combination on the gut mucosal barrier
licorice-yuanhua is one of the incompatible herbal pairs in the "Eighteen incompatible Medicaments" of traditional Chinese Medicine. In this study, Chemical compounds in licorice and yuanhua were used to treat the LS174T cells and iTRAQ labled proteomics study was conducted.
ORGANISM(S): Homo Sapiens 
2020-04-09 | PXD018456 |
ProteomicsSILAC experiments profiling of the proteome of WT and CobB KO E.coli
SILAC experiments profiling of the proteome of WT and CobB KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030345 |
ProteomicsSILAC experiments profiling of the proteome of WT and YiaC KO E.coli
SILAC experiments profiling of the proteome of WT and YiaC KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030346 |
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