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The goal of this experiment was to validate a classification model built on other bulk transcriptomic data that was capable of identifying in vitro stimulated M-CSF differentiated macrophages. Specifically, the classification model was capable of distinguishing: M-LPSearly (2-4 hours) M-LPSlate (18...
ORGANISM(S): Homo sapiens 
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
This study aimed to investigate the cardioprotective mechanism of baicalin (BAI) against myocardial ischemia-reperfusion injury (MIRI) in rats. We performed RNA-seq on left ventricular myocardial tissue from three groups: Sham (vehicle control), I/R (ischemia-reperfusion injury model), and I/R+BAI (...
ORGANISM(S): Rattus norvegicus 
TLR4 deficiency attenuates kidney injury after ischemic reperfusion as measured by both renal function and morphology. To better understand the role of TLR4 during the acute kidney injury, we used DNA microarray to identify genes that were differentially expressed on kidneys in wildtype B10 mice and...
ORGANISM(S): Mus musculus 
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