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After positive selection in the thymus, the newly generated single positive (SP) thymocytes are phenotypically and functionally immature and undergo apoptosis upon antigen stimulation. In the thymic medullary microenvironment, SP cells progressively acquire immunocompetence. Negative selection to r...
ORGANISM(S): Mus musculus 
Background: Importin 7 (IPO7), a karyopherin-β protein, is involved in various tumorigenesis and progression abilities by mediating the nuclear import of oncoproteins. However, the exact biological functions and IPO7 remain to be further elucidated. Materials and Methods: TCGA and GEO datasets were...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026995 | Pride
Using microRNA-Seq, we examined the alteration of microRNA expression profiles in the nucleus accumbens of methamphetamine-sensitized and saline-control mice. Nucleus accumbens lysate from eight mice of each group were pooled as one sample. Two RNA samples from each group were prepared and were then...
ORGANISM(S): Mus musculus 
Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao W, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia C, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan R, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi N, Mertins P, Carr SA, Rouleau G, ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-21 | MSV000080975 | MassIVE
Singapore grouper iridovirus (SGIV) is the major agent that causes severe iridovirus diseases in grouper maricluture. Based on the genomic information, a DNA microarray, containing probes corresponding to 162 putative SGIV open reading frames (ORFs) was constucted. The viral microarrays wereused to ...
ORGANISM(S): Epinephelus coioides 
Using ssRNA-seq, we examined the alteration of transcription profiles in the nucleus accumbens of methamphetamine-sensitized mice. Methamphetamine was a commonly abused psychostimulant. Repeated exposure to methamphetamine elicited long-lasting cellular and molecular changes, including the aberrant ...
ORGANISM(S): Mus musculus 
Our study focuses on searching for novel genes involved in cholesterol metabolism through genome-wide screening, RNA-seq, proteome and lipidomic.This project maily focus on the proteomics of LDLR and HMGCR double knock out human HepG2 cells.
ORGANISM(S): Homo sapiens (Human) 
2025-02-24 | PXD052324 | Pride
Singapore grouper iridovirus (SGIV) is the major agent that causes severe iridovirus diseases in grouper maricluture. Based on the genomic information, a DNA microarray, containing probes corresponding to 162 putative SGIV open reading frames (ORFs), was constructed to map the viral gene transcripti...
ORGANISM(S): Iridovirus 
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