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ProteomicsSsrp1 co-immunoprecipitation and mass spectrometry
Endogenous retroviruses (ERVs) were usually silenced by various histone modifications on histone H3 variants and respective histone chaperones in embryonic stem cells (ESCs). However, it is still unknown whether chaperones of other histones could repress ERVs. Here, we show that H2A/H2B histone chap...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-24 | PXD017351 | Pride
Ssrp1 Co-immunoprecipitation Mass spectrometry Esc 
ProteomicsA rapid and convenient sample treatment method based on the dissolvable polyacrylamide gel for S-acylation proteomics
S-acylation, dissolvable gel, sample treatment, proteomics
ORGANISM(S): Mus Musculus 
2024-06-04 | PXD052808 |
ProteomicsComprehensive N-Glycomics Profiling of Urinary Extracellular Vesicles Identifies a Novel Biomarker Panel for Diagnosis of Bladder Cancer
Bladder cancer (BC) is the most common urologic malignancy, facing enormous diagnostic challenges.Urinary extracellular vesicles (EVs) is a particularly promising source for developing diagnostic markers for bladder cancer because of the direct contact between urine and bladder. We investigate bioma...
ORGANISM(S): Homo Sapiens 
2024-11-14 | PXD057882 |
ProteomicsProteomic and Acetylome Alterations in Obesity-related Osteoarthritic Mouse Cartilage
Male mice aged 4 weeks were housed under controlled conditions and assigned to either a normal diet or a high-fat diet for 16 weeks to establish an obesity model. At 12 weeks, osteoarthritis was induced using the destabilization of the medial meniscus procedure under anesthesia, while sham-operated ...
ORGANISM(S): Mus Musculus 
2025-04-08 | PXD062707 |
ProteomicsQuantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B-related hepatocellular carcinoma
Lysine acetylation (Kac) as an important post-translational modification of histone is essential for gene expression regulation in hepatocellular carcinoma (HCC), however the atlas of whole acetylated proteins for HCC tissue and the difference of protein acetylation between human normal and HCC tiss...
ORGANISM(S): Homo Sapiens 
2020-10-24 | PXD022161 |
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