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ProteomicsFBXO3-mediated DUSP9 ubiquitination promotes leukemia stem cell maintenance and tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Eradicating leukemic stem cells (LSCs) and overcoming tyrosine kinase inhibitor (TKI) resistance is urgent for chronic myeloid leukemia (CML) treatment. We find that F-box protein 3 (FBXO3) is highly upregulated in CD34+ CML stem cells from TKI-resistant patients and identify it as an innovative CML...
ORGANISM(S): Homo sapiens (Human) 
2026-01-25 | PXD073522 | Pride
Tkis resistance Fbxo3 Cml-lscs Dusp9 Chronic myeloid leukemia 
UnknownDynamics in the resistant and susceptible peanut (Arachis hypogaea L.) root transcriptome on infection with the Ralstonia solanacearum.
Not available
S-EPMC4300042 | biostudies-literature
UnknownGenome-wide association study dissects the genetic architecture of seed weight and seed quality in rapeseed (Brassica napus L.).
Not available
S-EPMC4131830 | biostudies-literature
UnknownAnalysis of expression sequence tags from a full-length-enriched cDNA library of developing sesame seeds (Sesamum indicum).
Not available
S-EPMC3311628 | biostudies-literature
ProteomicsStructural Basis for Psilocybin Biosynthesis
To validate the pyruvoyl prosthetic group instead of the serine residue that exists in the N-terminal of the α-chain within the mature PsiD enzyme
ORGANISM(S): Candida albicans (Yeast) 
2025-03-15 | PXD061358 | Pride
Lc-ms/ms Psilocybin 
UnknownIllustration of the variation in the content of flavanone rutinosides in various citrus germplasms from genetic and enzymatic perspectives.
Not available
S-EPMC8788359 | biostudies-literature
ProteomicsComparative proteomic analysis of the brain and colon in three rat models of irritable bowel syndrome
Background: Irritable bowel syndrome (IBS) has been gradually recognized as a disorder of the brain-gut interaction, but the molecular changes in the brain and colon that occur in disease development remain poorly understood. We employed proteomic analysis to identify differentially expressed protei...
ORGANISM(S): Rattus Rattus 
2020-01-15 | PXD017099 |
UnknownEnhanced triacylglycerol production in the diatom Phaeodactylum tricornutum by inactivation of a Hotdog-fold thioesterase gene using TALEN-based targeted mutagenesis.
Not available
S-EPMC6231261 | biostudies-literature
UnknownDeep learning from "passive feeding" to "selective eating" of real-world data.
Not available
S-EPMC7603327 | biostudies-literature
UnknownAutomated detection of retinal exudates and drusen in ultra-widefield fundus images based on deep learning.
Not available
S-EPMC9307785 | biostudies-literature
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