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TranscriptomicsDusp9 expression and function in dendritic cells
Plasmacytoid dendritic cells (pDC) efficiently produce large amounts of type I interferon in response to TLR7 and TLR9 ligands, whereas conventional DCs (cDC) predominantly secrete high levels of the cytokines IL-10 and IL-12. The molecular basis underlying this distinct phenotype is not well unders...
ORGANISM(S): Mus musculus 
2015-06-26 | E-GEOD-54120 | biostudies-arrayexpress
ProteomicsFBXO3-mediated DUSP9 ubiquitination promotes leukemia stem cell maintenance and tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Eradicating leukemic stem cells (LSCs) and overcoming tyrosine kinase inhibitor (TKI) resistance is urgent for chronic myeloid leukemia (CML) treatment. We find that F-box protein 3 (FBXO3) is highly upregulated in CD34+ CML stem cells from TKI-resistant patients and identify it as an innovative CML...
ORGANISM(S): Homo sapiens (Human) 
2026-01-25 | PXD073522 | Pride
Tkis resistance Fbxo3 Cml-lscs Dusp9 Chronic myeloid leukemia 
TranscriptomicsDusp9 expression and function in dendritic cells
Plasmacytoid dendritic cells (pDC) efficiently produce large amounts of type I interferon in response to TLR7 and TLR9 ligands, whereas conventional DCs (cDC) predominantly secrete high levels of the cytokines IL-10 and IL-12. The molecular basis underlying this distinct phenotype is not well unders...
ORGANISM(S): Mus musculus 
2015-06-26 | GSE54120 | GEO
GenomicsDUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells
DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells
PRJNA283520 | ENA
UnknownDownregulation of DUSP9 Promotes Tumor Progression and Contributes to Poor Prognosis in Human Colorectal Cancer.
Not available
S-EPMC7538709 | biostudies-literature
GenomicsRNA sequencing of Dusp9 and Klhl13 mutants in 1.8 female mouse embryonic stem cells (mESCs)
RNA sequencing of Dusp9 and Klhl13 mutants in 1.8 female mouse embryonic stem cells (mESCs)
PRJNA596761 | ENA
UnknownCaffeine ameliorates metabolic-associated steatohepatitis by rescuing hepatic Dusp9.
Not available
S-EPMC11815699 | biostudies-literature
UnknownInhibition of miR-194-5p avoids DUSP9 downregulation thus limiting sepsis-induced cardiomyopathy.
Not available
S-EPMC11366749 | biostudies-literature
UnknownDUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.
Not available
S-EPMC5524993 | biostudies-literature
UnknownThe dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development.
Not available
S-EPMC1234323 | biostudies-literature
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