To screen the differentially expressed genes between responders(Rs) and nonresponders(NRs) in CHB patients treated with IFN-α, and to explore the molecular basis for treatment failure.Expression profiling was performed on percutaneous needle liver biopsy specimens taken before therapy.Gene expressio...
We generated a P4ha2 knock-out mouse line (C57BL/6) by using CRISPR-Cas9 system. By mass spectrum, reduced proline hydroxylation was observed in collagens isolated from skin, sclera and cornea of P4ha2-/- mice.
A four-dimensional independent data acquisition (4D-DIA) proteomic was performed to determine the differentially expressed proteins in pleural effusion samples collected from ung adenocarcinoma MPE, BPE (tuberculosis pleural effusion (TPE) and parapneumonic effusion (PPE)).
The BasS / BasR two-component system in E. coli affects the sensitivity of E. coli to class IIa bacteriocins by regulating tricarboxylic acid cycle related proteins
This study utilizes quantitative proteomics to investigate the impact of the cobQ deletion (ΔahcobQ) on the global protein expression profile in A. hydrophila.