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ProteomicsProteotoxicity caused by perturbed protein complexes underlies hybrid incompatibility
Dobzhansky-Muller incompatibilities represent a major driver of reproductive isolation between species. They are caused when two or more interacting components encoded by alleles from different species cannot function properly when mixed. At incipient stages of speciation, complex incompatibilities ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-05 | PXD028358 | Pride
Epistasis Protein complex Proteotoxicity Proteostasis Speciation Genetic incompatibility 
MetabolomicsMultiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

BACKGROUND: Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA). However, the pathogenesis, host-pathogen interaction, and diagnostic markers ...

2022-06-24 | MTBLS3306 | MetaboLights
ProteomicsProteomics of adult and metacercariae of Metorchis orientalis
We used proteomics to compare the differential protein expression between adult and metacercariae stage of Metorchis orientalis. Three biological replicates were set up at each stage for protein analysis using Nano HPLC.
ORGANISM(S): Metorchis Orientalis 
PXD029022 |
ProteomicsTargeting PILRα, an immune checkpoint mediating T cell suppression, for cancer immunotherapy
One of the most successful therapies in cancer treatment involves immune checkpoint blockade using the anti-programmed death-1 (anti-PD-1)/programmed death-ligand 1 (PD-L1) antibody, which targets the interaction between tumors and T cells. However, the overall response rate is < 30% in patients wit...
ORGANISM(S): Homo Sapiens 
2024-01-25 | PXD048903 |
UnknownRisk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
Not available
S-EPMC6306365 | biostudies-literature
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