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MetabolomicsTFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis
The mechanisms underlying cancer metastasis remain poorly understood. Here, we report that TFAM deficiency rapidly and stably induced spontaneous lung metastasis in mice with liver cancer. Interestingly, unexpected polymerization of nuclear actin was observed in TFAM-knockdown HCC cells when cytoske...
2022-06-23 | MTBLS4307 | MetaboLights
ProteomicsMS characterization of SARS-CoV-2 NCP PTM profile
Glycosylation and PTM profile of NCP from SARS-CoV-2
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2021-04-14 | PXD025404 |
ProteomicsHSV1 ICP0 associated ubiquitination modulation in N2A neuron cells
Proteome-wide survey of ubiquitination modulation in N2A neuron cells in response to HSV1 ICP0 transfection and HSV1 infection
ORGANISM(S): Homo Sapiens Human Herpesvirus 1 Mus Musculus 
2021-01-17 | PXD019782 |
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
ProteomicsChemical proteomic profiling of protein N-homocysteinylation with a thioester probe
We performed quantitative chemical proteomics to identify more than 800 N-homocysteinylated proteins as well as 304 N-homocysteinylated sites directly from HTL-treated HeLa cells.
ORGANISM(S): Homo Sapiens 
2024-10-09 | PXD056640 |
ProteomicsComparison of Salmonella proteome between different serovars
This study compares the proteome of Salmonella enterica serovars Typhimurium, Typhi, Enteritidis, Paratyphi A, etc. under the SPI-1- and SPI-2-inducing growth conditions.
ORGANISM(S): Salmonella Sp. Wt 
2020-10-30 | PXD022254 |
ProteomicsComparative proteomic Analysis of wheat roots
Root is of vital important in acquiring nutrients and water from soils. Uncovering the regulatory mechanism of wheat root growth is of great help for genetic improvement of roots traits. A comparative proteomic analysis was performed. Expressed proteins were identified under CK and LN conditions. Pr...
ORGANISM(S): Triticum Aestivum 
2018-03-19 | PXD008793 |
ProteomicsCREB3 suppresses hepatocellular carcinoma progression by depressing AKT signaling through competitively binding with INSR and transcriptionally activating RBM38
CREB3 is suggested to interact with many proteins. We explored the potential binding proteins using co-IP.
ORGANISM(S): Homo Sapiens 
2024-05-27 | PXD052604 |
Proteomicsdevelopment of prognostic biomarkers for HBV-related acute-on-chronic liver failure
development of prognostic biomarkers for HBV-related acute-on-chronic liver failure
ORGANISM(S): Homo Sapiens 
2020-03-07 | PXD017928 |
ProteomicsDDX5-sIL-36R in keratinocytes controls skin inflammation
The DEAD-box (DDX) proteins function in diverse cellular processes including RNA alternative splicing, and are linked to immune-mediated diseases. However, little is known about the roles of DDXs in skin inflammatory diseases. Here, we show that DDX5, one of the founding members of the DDX RNA helic...
ORGANISM(S): Homo Sapiens 
2020-09-09 | PXD021379 |
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