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UnknownTranscriptomics and metabolomics revealed the molecular basis of the color formation in the roots of <i>Panax notoginseng</i>.
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S-EPMC11459398 | biostudies-literature
ProteomicsThe deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
Spermiogenesis defines the final phase of male germ cell differentiation. Multiple deubiquitinating enzymes have been linked to spermiogenesis, yet the impacts of deubiquitination on spermiogenesis remain poorly characterized. Here, we investigated the function of UAF1 in mouse spermiogenesis and ma...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-07 | PXD046120 | Pride
Uaf1 usp1 male infertility spermiogenesis deubiquitylation 
ProteomicsAvian pathogenic Escherichia coli infection causes infiltration of heterophilic granulocytes of chick tracheal by the complement and coagulation cascades pathway
Tracheal mucosal epithelial cells were scraped at 12 and 24 hours of infection, frozen in liquid nitrogen and stored at -80°C. The cells were sent to a biotechnology company for TMT quantitative proteomic analysis. The cells were sent to a biotech company for TMT quantitative proteomics analysis.
ORGANISM(S): Gallus gallus (Chicken) 
2024-01-26 | PXD044411 | Pride
Avian pathogenic escherichia coli  ae17  tmt-sequencing  complement and coagulation cascades pathways  pathogenicity 
ProteomicsBioorthogonal Photocatalytic Proximity Labeling in Primary Living Samples
In situ profiling of subcellular proteomic networks in primary and living systems, such as primary cells from native tissues or clinic samples, is crucial for the understanding of life processes and diseases, yet challenging for the current proximity labeling methods (e.g., BioID, APEX) due to their...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-05-24 | PXD045791 | Pride
Proximity labeling Mitochondria Bioorthogonal chemistry Photocatalysis 
ProteomicsProteomic analysis of human circulating neutrophils upon multi states
Neutrophils exhibited remarkable plasticity and heterogenicity in both homeostasis and pathology conditions. Here, we conducted a “multi-states” proteomics methodology to explore how neutrophils respond upon infection and inflammation stress including bacterial analog LPS, virus analog Poly(I:C), pr...
ORGANISM(S): Homo Sapiens 
2024-12-23 | PXD059138 |
ProteomicsClinical proteomics analysis using Data Independent Acquisition-Mass Spectrometry (DIA-MS) identified classifiers for molecular characterization of Lymphoma
In this study, we conducted a proteomics analysis on 109 fresh-frozen lymph node samples from clinical patients, covering a comprehensive suite of lymphoma subtypes including B-NHL, T-NHL, HL, Lymphadenitis, Tumor metastatic lymph node (TLN), and Non-neoplastic lymph node (TNM: N0).
ORGANISM(S): Homo Sapiens 
2020-01-15 | PXD017096 |
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2020-07-30 | PXD020653 |
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