Sort   by:  
 Page size 
ProteomicsThe deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
Spermiogenesis defines the final phase of male germ cell differentiation. Multiple deubiquitinating enzymes have been linked to spermiogenesis, yet the impacts of deubiquitination on spermiogenesis remain poorly characterized. Here, we investigated the function of UAF1 in mouse spermiogenesis and ma...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-07 | PXD046120 | Pride
Uaf1 usp1 male infertility spermiogenesis deubiquitylation 
UnknownThe USP1-UAF1 complex interacts with RAD51AP1 to promote homologous recombination repair.
Not available
S-EPMC5053553 | biostudies-literature
UnknownPromotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex.
Not available
S-EPMC5381662 | biostudies-literature
UnknownThe USP1/UAF1 complex promotes double-strand break repair through homologous recombination.
Not available
S-EPMC3133424 | biostudies-literature
UnknownUSP1-UAF1 deubiquitinase complex stabilizes TBK1 and enhances antiviral responses.
Not available
S-EPMC5716033 | biostudies-literature
UnknownThe deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis.
Not available
S-EPMC10999478 | biostudies-literature
UnknownUAF1 deubiquitinase complexes facilitate NLRP3 inflammasome activation by promoting NLRP3 expression.
Not available
S-EPMC7695691 | biostudies-literature
UnknownA conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
Not available
S-EPMC5131612 | biostudies-literature
UnknownTargeting UAF1 Alleviate Neurotoxicity by Inhibiting APP/NLRP3 Axis-Mediated Pyroptosis and Apoptosis.
Not available
S-EPMC11971201 | biostudies-literature
ProteomicsATAD5-BAZ1B interaction modulates PCNA ubiquitination during DNA repair
Mono-ubiquitinated PCNA (mono-Ub-PCNA) is generated when replication forks stall and facilitates the DNA lesion bypass process. After resolving a replication stall, Ub-PCNA needs to be de-ubiquitinated to resume high-fidelity DNA synthesis. ATAD5 cooperates with UAF1-USP1 to de-ubiquitinate mono-Ub-...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050108 | Pride
Baz1b De-ubiquitination Dna repair Usp1 Smarca5 Atad5 Baz1b Uaf1 Pcna 
Sort   by:  
 Page size