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ProteomicsOverexpression of McHB7 Transcription Factor from Mesembryanthemum crystallinum Improves Plant Salt Tolerance
Mesembryanthemum crystallinum (common ice plant) is one of the facultative halophyte plants, and it serves as a model for investigating the molecular mechanisms underlying its salt stress response and tolerance. Here we cloned one of homeobox transcription factor (TF) gene McHB7 from ice plant, whic...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-08-11 | PXD033886 | Pride
Salt stress common ice plant proteomics 
TranscriptomicsTranscriptomics analysis of skeletal muscle in humans with heart failure
Heart failure is a multisystem syndrome caused by structural and functional defects in multiple tissues. The study aims to identify differentially regulated genes in skeletal muscle of heart failure patients. Here, we obtained biopsies from the pectoralis major muscle and performed RNA sequencing to...
ORGANISM(S): Homo sapiens 
2020-09-07 | E-MTAB-8531 | biostudies-arrayexpress
ProteomicsMulti-functions of McHB7 in Mesembryanthemum crystallinum responses to salt and drought stresses
Mesembryanthemum crystallinum (common ice plant) is one of the most important halophyte plants for plant stress biology research. In this study, we established an efficient Agrobacterium-mediated transformation method in ice plant and confirmed that ice plant can sustain gene overexpression for four...
ORGANISM(S): Mesembryanthemum crystallinum (Common ice plant) (Cryophytum crystallinum) 
2024-05-21 | PXD033521 | Pride
Salt stress  drought stress  proteomics 
TranscriptomicsIdentification of exercise-related genes in mice exposed to cigarette smoke
Cigarette smoke (CS) is the major risk factor for COPD and is linked to cardiopulmonary dysfunction. Exercise training, as part of pulmonary rehabilitation, is recommended for all COPD patients. It has several physiological benefits, but the involved mechanisms remain poorly defined. Here, we employ...
ORGANISM(S): Mus musculus 
2022-11-04 | E-MTAB-12256 | biostudies-arrayexpress
TranscriptomicsSex differences in skeletal muscle pathology in patients with heart failure and reduced ejection
Females with heart failure and reduced ejection fraction (HFrEF) have greater physical limitations and a lower quality of life compared to males, however, the role of non-cardiac mechanisms remains poorly resolved. We hypothesized that differences in skeletal muscle pathology between males and femal...
ORGANISM(S): Homo sapiens 
2024-07-12 | E-MTAB-14110 | biostudies-arrayexpress
UnknownA comparative analysis of Patient-Reported Expanded Disability Status Scale tools.
Not available
S-EPMC5015760 | biostudies-literature
TranscriptomicsCaloric restriction rejuvenates myofiber growth in heart failure
Heart failure with preserved ejection fraction (HFpEF) is characterised by a distinct but poorly understood in skeletal muscle pathology. In a rat model ZSF1, we identify impaired myonuclear accretion as a mechanism for ablated myofiber growth in HFpEF following resistance exercise intervention. Mus...
ORGANISM(S): Rattus norvegicus 
2025-01-19 | E-MTAB-12494 | biostudies-arrayexpress
UnknownWidespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease.
Not available
S-EPMC5302813 | biostudies-literature
UnknownInternet-Based Germline Genetic Testing for Men With Metastatic Prostate Cancer.
Not available
S-EPMC9928882 | biostudies-literature
UnknownA spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease.
Not available
S-EPMC10356953 | biostudies-literature
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