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ProteomicsDynamic changes in proteome and phosphoproteome following glutamate excitotoxicity in cultured primary cortical neurons
Excitotoxicity caused by over-stimulation of the ionotropic glutamate receptors is a key neuronal cell death process underpinning brain damage in acute and chronic neurological disorders such as ischaemic stroke, traumatic brain injury, and neurodegenerative diseases. Exactly how neurons die in exci...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-07 | PXD008353 | Pride
Neuron Phosphoproteome Proteome Excitotoxicity 
ProteomicsN-terminomics Analysis of Mouse cultured cortical neuron during excitotoxicity
Excitotoxicity is a primary pathological process directing neuronal cell death in both acute neurological disorders and neurodegenerative diseases such as ischemic stroke and Alzheimer’s disease. We use mouse cultured cortical neuron treated with 100uM of Glutamate for a model of excitotoxicity and ...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-07 | PXD040648 | Pride
N-term Excitotoxicity 
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