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ProteomicsUtilizing Liquid Biopsy-Derived Extracellular Vesicle Protein Biomarkers for Diagnosis and Prognostic Assessment in Lung Squamous Cell Carcinoma
In the context of pulmonary nodules detected in imaging, there is currently a lack of highly effective and non-invasive methods for both diagnosing and prognosticating lung squamous cell carcinoma (LUSC). Therefore, in this study, we explored the potential of plasma-derived extracellular vesicles (E...
ORGANISM(S): Homo Sapiens 
2023-12-18 | PXD047893 |
ProteomicsIntegrative proteomic characterization of human lung adenocarcinoma
Genomic studies of lung adenocarcinoma (LUAD) have advanced understanding of the disease’s biology and accelerated targeted therapy. However, proteomic characteristics of LUAD remain poorly understood. We carried out comprehensive proteomic analysis of 103 cases of LUAD in Chinese patients. Integrat...
ORGANISM(S): Homo Sapiens 
PXD020252 |
TranscriptomicsNCI-H1299 cell line transfected with human DENND2D and vector
Gene expression for NCI-H1299 cell line transfected with human DENND2D and vector (pcDNA3.1/V5-His TOPO TA vector) respectively. The microarray experiment was designed to perform four replicates for each H1299-DENND2D and H1299-vector sample. cRNA used in replication 1 and 2 was from the same label...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-16890 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiling of human lung at four developmental stages and lung adenocarcioma
It is gradually becoming a new aspect in research to search and explore embryo development for malignant information hidden in tumor cells. In this study, the gene expression profiles for human lungs at four developmental stages and lung adenocarcinoma (ADC) were depicted, respectively. The molecula...
ORGANISM(S): Homo sapiens 
2014-08-25 | E-GEOD-43767 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of tumor-adjacent histologically normal lung tissues from lung SCC patients
Tumor-adjacent noncancerous tissues often exhibited abnormalities on molecular levels, which is described as field effect of cancerization. Accumulated evidence demonstrated that filed effect may also play important role in cancer progression. In the present study, we found that the gene expression ...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-40588 | biostudies-arrayexpress
TranscriptomicsRNA-seq of rat dorsal root ganglia after ligation to investigate central nervous system transcriptomics in chronic pain using agnostic splice site discovery methods
The study pursued dual goals: To advance mRNA-seq bioinformatics towards unbiased transcriptome capture and to demonstrate its potential for discovery in neuroscience by applying the approach to an in vivo model of neurological disease. We found that 12.4% of known genes were induced and 7% were sup...
ORGANISM(S): Rattus norvegicus 
2010-05-01 | E-GEOD-20895 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of colorectal normal mucosa, adenoma and adenocarcinoma tissues
Approximately two decades ago, Vogelstein and Fearon proposed the adenoma-carcinoma sequence of sporadic CRC development and illustrated the accumulation of genetic alterations during the stepwise progression, thereby providing a guideline for clinical practice. Although the detection and excision o...
ORGANISM(S): Homo sapiens 
2015-10-16 | E-GEOD-41657 | biostudies-arrayexpress
TranscriptomicsGene expression in an EMT model using an immortalized bronchial epithelial cell line induced by TGF-M-NM-21
This study aimed to establish an epithelial-mesenchymal transition (EMT) model with an immortalized human bronchial epithelial cell line, M-BE, and to identify an EMT signature gene set. The TGF-M-NM-21-induced M-BE cells got spindle-shaped fibroblast-like morphology and lost the cell-cell contact, ...
ORGANISM(S): Homo sapiens 
2013-10-06 | E-GEOD-40374 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of colorectal normal mucosa, adenoma and adenocarcinoma tissues
Approximately two decades ago, Vogelstein and Fearon proposed the adenoma-carcinoma sequence of sporadic CRC development and illustrated the accumulation of genetic alterations during the stepwise progression, thereby providing a guideline for clinical practice. Although the detection and excision o...
ORGANISM(S): Homo sapiens 
2015-10-16 | E-GEOD-41655 | biostudies-arrayexpress
UnknownThe mechanism for the enhanced piezoelectricity in multi-elements doped (K,Na)NbO3 ceramics.
Not available
S-EPMC7873261 | biostudies-literature
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