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The aim of the study was to identify markers for the early diagnosis of endoprosthesis loosening, for the differentiation between wear-particle induced and septic loosening, as well as to gather new insights into the pathogenesis. 824 genes were differentially expressed with a fold change greater th...
ORGANISM(S): Homo sapiens 
Epithelial regeneration is modulated by chitin and chitinase activity
Epithelial regeneration is modulated by chitin and chitinase activity
Epithelial injury underlies fibrotic and inflammatory lung diseases during which regenerative responses become dysregulated or recurrently engaged. Although environmental exposures are risk factors for severe lung disease, specific drivers of persistent epithelial and immune dysfunction are poorly u...
ORGANISM(S): Mus musculus 
2024-12-31 | GSE275075 | GEO
Epithelial injury underlies fibrotic and inflammatory lung diseases during which regenerative responses become dysregulated or recurrently engaged. Although environmental exposures are risk factors for severe lung disease, specific drivers of persistent epithelial and immune dysfunction are poorly u...
ORGANISM(S): Mus musculus 
2024-12-31 | GSE275319 | GEO
Bees make honey from the nectar that they collect from flowers. The characteristics of honey are closely associated to original botanical species. Compare with sugars in honey, proteins are minor components but usually used as an important honey quality evaluation parameters. Flower-origin proteins ...
ORGANISM(S): Eriobotrya japonica Apis mellifera mellifera 
2019-02-15 | PXD010083 | Pride
Chitinases are ubiquitous enzymes involved in biomass degradation and chitin turnover in nature. Pseudomonas aeruginosa (PA), an opportunistic human pathogen, expresses ChiC, a secreted glycoside hydrolase 18 (GH18) family chitinase. Despite speculation about ChiC's role in PA disease pathogenesis, ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 Bacteria 
2024-04-30 | PXD048596 | Pride
Particulate Matter10-induced airway inflammation and fibrosis can be regulated by chitinase-1 suppression
Function analysis and characterisation of a novel chitinase, MdCht9, in Musca domestica
Particulate matter10 (PM10) can induce airway inflammation and fibrosis. Chitinase-1 is recently known to have key roles in inflammation and fibrosis. We aimed to investigate the effects of chitinase-1 inhibitor in PM10-treated murine models. PM10 and/or OVA-induced airway inflammation and fibrosis ...
ORGANISM(S): Mus musculus 
2023-01-05 | GSE222111 | GEO
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