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UnknownIdentification of high affinity HER2 binding antibodies using CHO Fab surface display.
Not available
S-EPMC5892863 | biostudies-literature
TranscriptomicsCharacterization of A Novel CRAC Inhibitor that Potently Blocks Human T cell Activation and Effector Functions
Store operated calcium entry (SOCE) downstream of T cell receptor (TCR) activation in T lymphocytes has been shown to be mediated mainly through the Calcium Release Activated Calcium (CRAC) channel. Here, we compared the effects of a novel, potent and selective CRAC inhibitor, 2,6-Difluoro-N-{5-[4-m...
ORGANISM(S): Homo sapiens 
2013-01-31 | E-GEOD-43210 | biostudies-arrayexpress
UnknownReversible covalent inhibition of eEF-2K by carbonitriles.
Not available
S-EPMC6482285 | biostudies-literature
TranscriptomicsThe responses of astrocytes stimulated by extracellular a-synuclein
Abnormal neuronal aggregation of a-synuclein is implicated in the development of Parkinson’s disease. Glial cells also show extensive a-synuclein pathology and are thought to contribute to disease progression. However, the mechanism that produces the glial a-synuclein pathology and the interaction b...
ORGANISM(S): Rattus norvegicus 
2010-01-11 | E-GEOD-11574 | biostudies-arrayexpress
UnknownProgerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells.
Not available
S-EPMC5973135 | biostudies-literature
UnknownChromatin changes in SMARCAL1 deficiency: A hypothesis for the gene expression alterations of Schimke immuno-osseous dysplasia.
Not available
S-EPMC5215361 | biostudies-literature
UnknownLipid insertion domain unfolding regulates protein orientational transition behavior in a lipid bilayer.
Not available
S-EPMC4554884 | biostudies-literature
TranscriptomicscDNA microarray analysis of splenic B220+CD138+ plasma cells from K/BxNsf and K/BxN mice
Long-lived plasma cells (LLPCs) develop under the help of follicular helper T (Tfh) cells and reside mainly in the bone marrow. However, these cells are unusually abundant in the spleen of several autoimmune models including K/BxNsf mice, yet their pathogenic impact remains unknown. To investigate a...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-66947 | biostudies-arrayexpress
UnknownExhaustive Exercise and Post-exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists.
Not available
S-EPMC7769812 | biostudies-literature
TranscriptomicsGenome-wide analysis of cellular NMD substrates that regulated by Upf1, PNRC2 or CTIF in HeLa cell
The first round of translation occurs on mRNAs bound by nuclear cap-binding complex (CBC), which is composed of nuclear cap-binding protein (CBP) 80 and 20. During this round of translation, aberrant mRNAs are recognized and downregulated in abundance by nonsense-mediated mRNA decay (NMD), which is ...
ORGANISM(S): Homo sapiens 
2012-07-22 | E-GEOD-37538 | biostudies-arrayexpress
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