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ProteomicsDynamic tracking and identification of tissue-specific secretory proteins in the circulation of live mice
Accurate analysis of tissue-specific secretory proteins in blood plasma can provide valuable information regarding therapeutic target development but current approaches are mostly limited to ex vivo proteomic analysis. Here, we developed an in situ secretory protein labeling technology using endopla...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-08-06 | PXD025141 | Pride
Proteomics Proximity labeling Turboid 
ProteomicsTissue-specific in vivo mitochondrial matrix proteome profiling in mouse
Targeting proximity labeling enzymes to specific cellular locations is a viable strategy for profiling subcellular proteomes with minimal perturbance to normal physiology. Here, we generate transgenic mice expressing a mitochondrial matrix-targeted ascorbate peroxidase (MTS-APEX2) to enable analysis...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2023-08-31 | PXD026793 | Pride
Coenzyme q Proximity labeling Mitochondrial proteome Apex Rtn4ip1 Nadph Muscle Lc-ms/ms 
ProteomicsParkinson's disease mouse brain proteome profiling
We compared the proteome from a vulnerable region (Substantia nigra pars compacta, SNc) of wild-type and Parkinsonian mice to that of an adjacent, less vulnerable, region (Ventral tegmental area, VTA) and identified several proteins which exhibited both spatiotemporal- and genotype-restricted change...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-12-25 | MSV000080437 | MassIVE
ProteomicsAn Anatomically Resolved Comprehensive Mouse Brain Proteome
A mouse brain protein atlas that covers 17 surgically distinctive neuroanatomical regions of the adult mouse brain, each less than 1mm3 in size.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-06-01 | MSV000079789 | MassIVE
ProteomicsInsights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis
Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in accumulation of phosphate and formation of hydroxyapatite microliths in the alveolar space. The single cell transcriptomic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-16 | MSV000091302 | MassIVE
UnknownObservation of quantum entanglement with top quarks at the ATLAS detector.
Not available
S-EPMC11410654 | biostudies-literature
UnknownTransforming jet flavour tagging at ATLAS.
Not available
S-EPMC12804921 | biostudies-literature
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