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TranscriptomicsPrognostic signature of epithelial-mesenchymal transition in breast cancer
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis. Using breast cancer cell lines as a model system, we sought to discover gene-expression signatures of ...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-13915 | biostudies-arrayexpress
TranscriptomicsOrganogenic nodule formation from internodes of Humulus lupulus
Transcriptional profiling of hop samples throughout in vitro culture on medium with sucrose and hormones IAA and BAP Study of gene expression involved in stress response during in vitro culture and in organogenic nodule formation Hop (Humulus lupulus L.) is an economically important plant forming ...
ORGANISM(S): Humulus lupulus 
2008-09-01 | E-GEOD-12339 | biostudies-arrayexpress
TranscriptomicsGene expression in S1 panicles of Ubi1:AtJMT transgenic plants and drought-treated nontransgenic rice plants
To identify genes that are regulated by MeJA and drought, global expression profilings were performed on panicles from Ubi1:AtJMT, drought-treated NT, and untreated NT plants. The underlying assumption of this approach was that high levels of MeJA produced either by overexpression of AtJMT in the tr...
ORGANISM(S): Oryza sativa 
2009-07-09 | E-GEOD-14508 | biostudies-arrayexpress
UnknownIntegrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.
Not available
S-EPMC4062710 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis Col-0 and pil5 imbibed seeds after far-red or far-red/red light irradiation.
PIL5 is a key negative regulator of phytochrome mediated seed germination and PIL5 protein is degraded by red light irradiation through phytochrome. The microarray aimed to find various red light-regulated genes and PIL5-regulated genes in the imbibed seeds. Experiment Overall Design: Col-0 and pil5...
ORGANISM(S): Arabidopsis thaliana 
2010-01-19 | E-GEOD-14374 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of SHP -/- knockout mouse transcriptome
Goal of this study is to identify annotated and non-annotated genes transcriptionally regulated by small heterodime partner (SHP, Nrob2) expression. Liver 5' capped RNA samples from three SHP -/- and three wild type mice were sequenced with Illumina GAII sequencer.
ORGANISM(S): Mus musculus 
2013-10-22 | E-GEOD-43893 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse skin after acute withdrawal of TERT
TERT is an essential protein component of telomerase, a ribonuclearprotein complex that protects chromosomal ends. Ectopic expression of TERT in mouse skin activates hair follicle stem cells and induces active growth phase of hair cycles, called anagen. This activity of TERT is independent of its re...
ORGANISM(S): Mus musculus 
2008-06-17 | E-GEOD-9725 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses to water deficit and Xylella fastidiosa (Pierce's disease) in Vitis vinifera
Pierce's disease, caused by the bacterium Xylella fastidiosa, is one of the most devastating diseases of cultivated grapes. To test the long-standing hypothesis that Pierce's disease results from pathogen-induced drought stress, we used the Affymetrix Vitis GeneChip to compare the transcriptional re...
ORGANISM(S): Vitis vinifera 
2013-02-12 | E-GEOD-44213 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of breast cancer cell lines defines relevant tumor models (gene expression)
Summary: Breast cancer cell lines have been used widely to investigate breast cancer pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease, and it is important to understand how well and which cell lines best model that diversity. In particular, microarray studies ha...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-15361 | biostudies-arrayexpress
TranscriptomicsHemangioblast skewing from embryonic stem(ES) cells by defined factors
Successful derivation of a specific cell lineage from pluripotent stem cells will tremendously facilitate the clinical usage of pluripotent stem derived somatic cells. Herein, we demonstrate that ER71/Etv2, GATA2 and Scl form a core network in hemangioblast development and that transient co-expressi...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-45147 | biostudies-arrayexpress
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