Chong Mark S K MS

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Unknown (10)
Metabolomics (3)
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Schizophyllum commune H4-8 (1)
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MetaboLights (3)
pride (1)

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Diffuse midline glioma (1)

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Mass spectrometry (3)
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Tandem Gas Chromatography MS - (2)
Tandem Gas Chromatography MS - positive (1)
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2023 (2)
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CHEBI ID

CHEBI:151122 (2)
CHEBI:151029 (2)
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CHEBI:84271 (2)
CHEBI:151023 (2)
CHEBI:151084 (2)
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CHEBI:84867 (2)
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CHEBI:46905 (2)
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CHEBI:36632 (2)
CHEBI:28385 (2)
CHEBI:33017 (2)

Metabolite Name

Diacetone alcohol (2)
N-Acetylglutamic acid (2)
Acetophenone (2)
Guanosine monophosphate (2)
Stearic acid (2)
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L-Aspartic acid (2)
L-Phenylalanine (2)
Ornithine (2)
Lumichrome (2)
L-Threonine (2)
Guanine (2)
L-Methionine (2)
L-Proline (2)
L-Serine (2)
2,6-Dimethylnonane (1)
Triacontanoic acid methyl ester (1)

Release Date

2023 (2)
2022 (2)
2025 (1)
2024 (1)
2021 (1)
2020 (1)
2019 (1)
2016 (1)

Lab affiliation

1. Cancer Signalling Research Group, School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW, AUSTRALIA 2. Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, AUSTRALIA 3. Paediatric Program, Mark Hughes Foundation Centre for Brain Cancer Research, College of Health, Medicine, and Wellbeing, Callaghan, NSW, AUSTRALIA (1)

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Metabolic Dynamics in Escherichia coli-Based Cell-Free Systems

The field of metabolic engineering has yielded remarkable accomplishments in using cells to produce valuable molecules, and cell-free expression (CFE) systems have the potential to push the field even further. However, CFE systems still face some outstanding challenges, including endogenous metaboli...

2023-02-22 | MTBLS2630 | MetaboLights

HERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION

Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...

2025-04-03 | MTBLS5163 | MetaboLights

Metabolic Profiling of Escherichia coli-Based Cell-Free Expression Systems for Process Optimization

Biotechnology has transformed the production of various chemicals and pharmaceuticals due to its efficient and selective processes, but it is inherently limited by its use of live cells as 'biocatalysts.' Cell-free expression (CFE) systems, which use a protein lysate isolated from whole cells, have ...

2020-06-02 | MTBLS1079 | MetaboLights

ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma

Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPGs), are the most lethal of all childhood cancers. Palliative radiotherapy is the only proven life-prolonging treatment, with patient survival 9-11 months. ONC201 shows preclinical and emerging clinical efficacy in DIPG. ...

ORGANISM(S): Homo sapiens (Human)

2023-05-25 | PXD036245 | Pride