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TranscriptomicsGene expression profiles obtained from laser-microdissected human choroid plexus papilloma cells
Gene expression profiles generated from human tumor cells laser-microdissected from surgical samples of seven choroid plexus papillomas (Grade I WHO) as eight samples of epithelial cells lasermicrodissected from normal choroid plexus obtained at autopsy. Choroid plexus tumors are rare pediatric brai...
ORGANISM(S): Homo sapiens 
2009-02-01 | E-GEOD-14098 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis and comparison of E15 and adult rat lateral ventricular choroid plexus epithelial cells.
Transcriptome analysis of lateral ventricular choroid plexus epithelial cells of embryonic day 15 (E15) and adult control Sprague-Dawley rats. We analyzed total RNA extracted from plexus epithelial cells from 6 pooled samples (3 E15, 3 adult) using the Illumina HiSeq 2000 platform.
ORGANISM(S): Rattus norvegicus 
2013-09-16 | E-GEOD-44072 | biostudies-arrayexpress
TranscriptomicsGene expression study in choroid plexus
The choroid plexus (CP) constitutes one of the blood–brain barriers – the blood cerebrospinal fluid barrier. It is formed by a monolayer of epithelial cells located within the brain ventricles and in addition to be responsible for the formation of the cerebrospinal fluid (CSF) is ideally positioned ...
ORGANISM(S): Mus musculus 
2010-08-19 | E-GEOD-23714 | biostudies-arrayexpress
TranscriptomicsIn Vitro Transcriptome Analysis of Porcine Plexus Epithelial Cells in Response to Streptococcus suis: Functions of the Choroid Plexus in Antimicrobial Defense
We used microarrays to detail the global gene expression changes following apical infection of porcine choroid plexus epithelial cells (PCPEC) with Streptococcus suis (S. suis) We compared PCPEC either un-treated or infected with wild-type S. suis strain 10 or the acapsular strain 10cpsDEF, respecti...
ORGANISM(S): Sus scrofa 
2011-08-14 | E-GEOD-23751 | biostudies-arrayexpress
ProteomicsLocalized Proteomic Differences in Choroid Plexus of Alzheimers Disease and Epilepsy Patients
Alzheimers disease and epilepsy are reciprocally related. Among sporadic AD patients, seizures occur in 10-22 percent, and subclinical epileptiform abnormalities occur in 22-5 percent. Cognitive deficits, with prominent short-term memory impairments, occur in most epilepsy patients. Common neurophys...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-27 | MSV000091370 | MassIVE
ProteomicsProteomics profiling of pediatric choroid plexus tumors
Aggresome is a para nuclear inclusion body that functions as a storage compartment for misfolded proteins. Our previous work revealed the presence of aggresomes in pediatric choroid plexus tumors (CPT). CPTs are rare neoplasms comprised of three pathological subgroups; choroid plexus carcinoma (CPC)...
ORGANISM(S): Homo sapiens (Human) 
2021-02-11 | PXD021076 | Pride
Human Carcinoma Cancer Choroid plexus Tissue Pappiloma Atypical Tumor Pediatric 
TranscriptomicsGene expression of the human choroid plexus epithelium (CPE)
We investigated the gene expression of the human CPE.We isolated CPE cells from healthy human donor choroid plexus tissues with laser dissection microscopy. Next, we performed RNA isolation, amplification, labeling and hybridization against 44k Agilent microarrays. We performed the microarrays again...
ORGANISM(S): Homo sapiens 
2013-09-27 | E-GEOD-49969 | biostudies-arrayexpress
TranscriptomicsComparison of the Global Gene Expression of Choroid Plexus and Meninges and Associated Vasculature under Control Conditions and after Pronounced Hyperthermia or Amphetamine Toxicity
These tissue were harvested to complement and extend the studies that generated GSE23093. They served 3 purposes; 1) identify genes important to choroid plexus function and compare them with those important for meninges and associated vasculature (MAV) function, 2) determine genes in the choroid pl...
ORGANISM(S): Rattus norvegicus 
2012-08-01 | E-GEOD-29733 | biostudies-arrayexpress
TranscriptomicsThe transcription factor Otx2 regulates choroid plexus development and function
The choroid plexuses (ChPs) are the main regulators of cerebrospinal fluid (CSF) composition and thereby also control the composition of a principal source of signaling molecules that is in direct contact with neural stem cells in the developing brain. The regulators of ChP development mediating the...
ORGANISM(S): Mus musculus 
2013-02-05 | E-GEOD-27630 | biostudies-arrayexpress
ProteomicsChoroid plexus proteome with and without LPS
Choroid plexus was isolated and pooled from the 5 mice after the perfusion with bromo phenol blue from 0 h and 6 h LPS treated mice. Proteins were isolated and trypsin digested and labelled with the NHS-porp (0h –LPS and 6h +LPS). Pre-fractionated using RP-HPLC and analysed on the Qexactive.
ORGANISM(S): Mus musculus (Mouse) 
2016-09-27 | PXD001347 | Pride
Lps Mouse Choroid plexus 
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