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TranscriptomicsIL-17A influences essential functions of the monocyte / macrophage lineage and is involved in advanced murine and human atherosclerosis
Atherosclerosis is a chronic inflammatory disease. Lesion progression is primarily mediated by cells of the monocyte/macrophage lineage. Interleukin-17A is a pro-inflammatory cytokine, which modulates immune cell trafficking and is involved inflammation in (auto)immune and infectious diseases. But t...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-60824 | biostudies-arrayexpress
MetabolomicsMechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes (Mouse data)
Evidence from several recent metabolomic studies suggests that increased concentrations of triacylglycerols (TAGs) with shorter (14-16 carbon atoms), saturated fatty acids are associated with insulin resistance and the risk of type 2 diabetes. Although causality cannot be inferred from association s...
2017-03-02 | MTBLS327 | MetaboLights
MetabolomicsMechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes (Human data)
Evidence from several recent metabolomic studies suggests that increased concentrations of triacylglycerols (TAGs) with shorter (14-16 carbon atoms), saturated fatty acids are associated with insulin resistance and the risk of type 2 diabetes. Although causality cannot be inferred from association s...
2015-10-05 | MTBLS162 | MetaboLights
TranscriptomicsMethylation profile of Hepatocellular Carcinoma
DNA methylation profiling of tumor and adjacent non-tumorous tissues of Hepatocellular Carcinoma (HCC) patients. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Samples included 59 tumors and 59 adjacent non-...
ORGANISM(S): Homo sapiens 
2014-12-10 | E-GEOD-57956 | biostudies-arrayexpress
TranscriptomicsExpression profile of Hepatocellular Carcinoma
Expression profiling of tumor and adjacent non-tumorous tissues of Hepatocellular Carcinoma (HCC) patients. Illumina HumanHT-12 V4.0 expression beadchip was used to obtain expression profiles across more than 31,000 annotated genes. Samples included 59 tumors and 59 adjacent non-tumorous samples. To...
ORGANISM(S): Homo sapiens 
2014-12-10 | E-GEOD-57957 | biostudies-arrayexpress
UnknownImpact of deep learning architectures on accelerated cardiac T1 mapping using MyoMapNet.
Not available
S-EPMC9532368 | biostudies-literature
ProteomicsMyeloid cell recruitment propels right ventricular dysfunction in HFpEF via sterile inflammation
This project characterizes chamber-specific proteomic remodeling in a murine three-hit HFpEF model that develops right ventricular dysfunction, using chow, hypoxia alone, and HFD+L-NAME as control conditions. The three-hit model (hypoxia, high-fat diet, and L-NAME) recapitulates key features of huma...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD074772 | Pride
Heart Mouse Hfpef Hypoxia 
ProteomicsSpleen proteomics data from high fat diet fed mice
The composition of the diet affects many processes in the body, including body weight and endocrine system. We have previously shown that dietary fat also affects the immune system. Mice fed high fat diet rich in polyunsaturated fatty acids survive S. aureus infection to a much greater extent than m...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-06 | PXD020365 | Pride
Polyunsaturated fatty acids Low fat diet Proteomics Saturated fatty acids Diet High fat diet Itraq 
UnknownAccelerated cardiac T1 mapping in four heartbeats with inline MyoMapNet: a deep learning-based T1 estimation approach.
Not available
S-EPMC8734349 | biostudies-literature
UnknownAccelerated Cardiac MRI Cine with Use of Resolution Enhancement Generative Adversarial Inline Neural Network.
Not available
S-EPMC10315558 | biostudies-literature
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