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ProteomicsComparative proteomic analysis of near isogenic lines for qDSI.4B.1 QTL on short arm of chromosome 4B conferring drought tolerance in wheat
This study conducted isobaric tags for relative and absolute quantitation (iTRAQ) proteomic analysis on near-isogenic lines (NILs) to shed light on the drought tolerance conferring qDSI.4B.1 QTL on short arm of chromosome 4B.
ORGANISM(S): Triticum aestivum (Wheat) 
2023-05-24 | PXD036534 | Pride
Nils Qtl Deps Drought stress Chromosome 4b Itraq Proteome Qrt-pcr 
TranscriptomicsThe HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
Transcriptional dysregulation has emerged as a core pathologic feature of Huntington's disease (HD), one of several triplet-repeat disorders characterized by movement deficits and cognitive dysfunction. Although the mechanisms contributing to the gene expression deficits remain unknown, therapeutic ...
ORGANISM(S): Mus musculus 
2010-12-27 | E-GEOD-26317 | biostudies-arrayexpress
TranscriptomicsHDAC inhibition imparts beneficial transgenerational effects in Huntington's disease mice via altered DNA and histone methylation
Increasing evidence has demonstrated that epigenetic factors can profoundly influence gene expression and, in turn, influence resistance or susceptibility to disease. Epigenetic drugs, such as histone deacetylase (HDAC) inhibitors, are finding their way into clinical practice, although their exact m...
ORGANISM(S): Homo sapiens 
2015-04-10 | E-GEOD-67733 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Azospirillum lipoferum 4B during its interaction with rice roots
Investigation of whole genome gene expression level changes in a Azospirillum lipoferum 4B associated to artificial roots, Oryza sativa japonica cv. Cigalon roots and Oryza sativa japonica cv. Nipponbare roots, compared to the strain grown in liquid culture. For each of the four condition, two repli...
ORGANISM(S): Azospirillum lipoferum 4B 
2014-01-01 | E-GEOD-42450 | biostudies-arrayexpress
UnknownWheat glutamine synthetase TaGSr-4B is a candidate gene for a QTL of thousand grain weight on chromosome 4B.
Not available
S-EPMC9271121 | biostudies-literature
UnknownA Bread Wheat Line with the Substituted Wild Emmer Chromosome 4A Results in Fragment Deletions of Chromosome 4B and Weak Plants.
Not available
S-EPMC11991261 | biostudies-literature
GenomicsBioCAP-Seq analysis of human chromosome 21 after its passage through either the mouse male germline
This study aims to investigate whether the passage of human chromosome 21 through the mouse male germline results in changes in the transcriptional deployment of the exogenous chromosome in the offspring generation. We used the Tc1 mouse model that stably carries almost an entire copy of human chrom...
ORGANISM(S): Mus musculus 
2016-11-16 | E-MTAB-4930 | biostudies-arrayexpress
UnknownA Major Quantitative Trait Loci Cluster Controlling Three Components of Yield and Plant Height Identified on Chromosome 4B of Common Wheat.
Not available
S-EPMC8786729 | biostudies-literature
TranscriptomicsChromosome wide analysis of parental allele specific chromatin and DNA methylation in mouse
This SuperSeries is composed of the following subset Series: GSE26720: Chromosome wide analysis of parental allele specific chromatin and DNA methylation GSE26891: Chromosome wide analysis of parental allele specific chromatin and DNA methylation along mouse distal chr7 GSE26892: Chromosome wide ana...
ORGANISM(S): Mus musculus 
2011-03-31 | E-GEOD-26947 | biostudies-arrayexpress
TranscriptomicsMethylation profiling in individuals with uniparental disomy identifies novel differentially methylated regions on chromosome 15
Methylation profiles of chr12-16 were generated by meDIP and array hybridisation in 3 cases with maternal uniparental disomy of chromosome 15, and three cases of paternal uniparental disomy of chromosome 15. Comparison of these profiles reveals differentially methylated (imprinted) regions on chromo...
ORGANISM(S): Homo sapiens 
2010-06-12 | E-GEOD-22188 | biostudies-arrayexpress
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