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TranscriptomicsAmplification of RANK- and c-Met-mediated signaling promotes metastatic colonization
We found that RANKL, expressed by cancer cells or derived from exogenous sources, consistently induced human prostate, breast, kidney, lung and liver cancer cells to colonize or metastasize to bone in an animal model of cancer bone metastasis. RANK-mediated signaling established a premetastatic nich...
ORGANISM(S): Homo sapiens 
2014-02-06 | E-GEOD-48432 | biostudies-arrayexpress
GenomicsC*01:02 new
C*01:02 new
PRJEB41094 | ENA
GenomicsHLA C 04 01 new
HLA C 04 01 new
PRJEB41599 | ENA
ProteomicsHepatitis C virus alters the morphology and function of peroxisomes.
Despite the introduction of effective treatments for hepatitis C in clinics, issues remain regarding the liver diseases induced by chronic hepatitis C virus (HCV) infection. HCV is known to disturb the metabolism of infected cells, especially lipid metabolism and redox balance, but the mechanisms le...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD044994 | Pride
Crispr-cas9 Peroxisome Apex2 Jfh1 Dbn3a Proximity biotinylation Ros Hepatitis c virus Hcv genotype 
TranscriptomicsTranscription profiling of C. elegans gene response to the pathogenic P. aeruginosa strain PA14.
Analysis of differential gene expression in C. elegans adults exposed to three different bacteria: E. coli strain OP50, wild-type P. aeruginosa PA14 and gacA mutant PA14. Samples were analyzed at 4 hours and 8 hours after exposure to the different bacteria. These studies identified C. elegans genes ...
ORGANISM(S): Caenorhabditis elegans 
2008-06-14 | E-GEOD-5793 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans daf-19(+) and daf-19(-) mutants
By screening for genes possessing canonical X-box sequences in promoters of three Caenorhabditis species, namely C. elegans, C. briggsae and C. remanei, we identified 93 genes (including known X-box regulated genes) that encode putative components of ciliated neurons in C. elegans and are subject to...
ORGANISM(S): Caenorhabditis elegans 
2008-06-14 | E-GEOD-6563 | biostudies-arrayexpress
ProteomicsDeciphering Black Extrinsic Tooth Stains composition in Children using metaproteomics
The present study focuses on the use of a metaproteomic approach to analyse Black Extrinsic Tooth Stains, a specific type of pigmented extrinsic substance, in a cohort of 96 Children. Metaproteomics is a powerful emerging technology that successfully enabled human protein and bacterial identificatio...
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD029245 | Pride
Saliva Dental plaque Oral pathology Metaproteomics 
TranscriptomicsPQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
Worms were exposed to 5 mM CoCl2 at the early day 1 of adulthood stage for 6 hr and 20 hr. Untreated worms were used as controls. Worms were collected, RNA isolated and hybridized on 4x44K C. elegans arrays (Agilent) at 60C overnight, as previously described 1). Three biological replicates were used...
ORGANISM(S): Caenorhabditis elegans 
2020-07-08 | GSE139562 | GEO
GenomicsPQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
PQM-1 and Cobalt Chloride dependent gene expression changes in C. elegans
PRJNA580256 | ENA
ProteomicsIdentification of ETV6 bound protein by affinity purification of ETV6-HA fusion protein in REH cells
To determine the protein partners of ETV6, we expressed ETV6 and HA-tagged ETV6 in Reh pre-B leukemic cells. Anti-HA magnetic beads were used for affinity purification of ETV6-HA (and ETV6 control) from the nuclear and cytoplasmic fraction. Following purification on-beads digest and LC-MS/MS experim...
ORGANISM(S): Homo sapiens (Human) 
2022-01-26 | PXD031001 | Pride
Leukemia All Etv6 
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