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ProteomicsCephalopod Chromatophore Proteomics
using the first annotated squid chromatophore proteome together with microscopy, we identified likely biochemical components of this reflective coloration as structural reflectin proteins distributed in cells that completely envelop each chromatocyte. Within the chromatocytes, where the pigment mole...
ORGANISM(S): Doryteuthis pealeii 
2019-03-05 | PXD011975 | Pride
Cephalopod molluscs Pigments Chromatophore Ω- crystallin 
ProteomicsCharacterization of R-loop-interacting proteins in embryonic stem cells reveals roles in ribosomal RNA processing and gene expression
Chromatin-associated RNAs have diverse roles in the nucleus. However, their mechanisms of action are poorly understood, in part due to the inability to identify proteins that specifically associate with chromatin-bound RNAs. Here, we address this problem for a subset of chromatin-associated RNAs tha...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-17 | PXD022697 | Pride
R-loop-interacting proteins Immunoprecipitation/mass spectrometry approach Rna-protein crosslinking 
ProteomicsPhosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
The intricate protein-chaperone network is vital for cellular function. Recent discoveries have unveiled the existence of specialized chaperone complexes called epichaperomes, protein assemblies orchestrating the reconfiguration of protein-protein interaction networks, enhancing cellular adaptabilit...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-10-17 | PXD050251 | Pride
Hsp90 Posttranslational modifications Epichaperome 
GenomicsHdac6 regulates Tip60-p400 function in stem cells (sequencing)
The Tip60 (also known as Kat5) lysine acetyltransferase functions broadly as a transcriptional co-activator that acetylates histones. In contrast, Tip60 functions in embryonic stem cells (ESCs) both to silence genes that promote differentiation and to activate genes required for proliferation. The m...
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-42209 | biostudies-arrayexpress
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