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ProteomicsDecoding the molecular complexity governing corneal wound closure in vivo
The cornea is the transparent tissue on the anterior surface of the eye. It is notably composed of a squamous stratified epithelium that forms a barrier protecting the ocular chamber. As the cornea is avascular, the delivery of nutrients and growth factors, required for corneal physiology, is essent...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD061492 | Pride
Epithelium Proteomics Cornea Lacrimal gland Epitranscriptomics Tears Transcriptomics 
UnknownAn iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions.
Not available
S-EPMC8324498 | biostudies-literature
ProteomicsTau Profiling of Brain Extracellular Vesicles Reveals PHF6 Peptide as Core for Pathological Tau Seeding in Alzheimer's Disease
EVs are bilipid spheres known for their role in cellular communication through transport of proteins, lipids, RNA and more. In the brain, EVs are directly released in the interstitial fluid surrounding neural cells and hence entitled brain-derived EVs (BD-EVs). Human BD-EVs of AD patients contain se...
ORGANISM(S): Homo Sapiens 
PXD067593 | panorama
UnknownA Scaled Proteomic Discovery Study for Prostate Cancer Diagnostic Markers Using ProteographTM and Trapped Ion Mobility Mass Spectrometry.
Not available
S-EPMC11311733 | biostudies-literature
UnknownNemvaleukin alfa, a modified interleukin-2 cytokine, as monotherapy and with pembrolizumab in patients with advanced solid tumors (ARTISTRY-1).
Not available
S-EPMC11580269 | biostudies-literature
UnknownCXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection.
Not available
S-EPMC12218331 | biostudies-literature
ProteomicsFunctional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease
Dysregulated proteolysis plays a pivotal role in the pathophysiology of inflammatory bowel disease. Nonetheless, the identity of overactive proteases released by human colonic mucosa remains unknown. Herein, we employed a serine protease-targeted activity-based probe (ABP) coupled with mass spectral...
ORGANISM(S): Homo sapiens (Human) 
2018-05-18 | PXD009450 | Pride
Inflammation Functional proteomics Activity-based probe Serine protease Inflammatory bowel disease 
UnknownVibration of effects in epidemiologic studies of alcohol consumption and breast cancer risk.
Not available
S-EPMC7266551 | biostudies-literature
TranscriptomicsFoxl1-Cre-marked Adult Hepatic Progenitors Have Clonogenic and Bi-Lineage Differentiation Potential - Time Course
The winged helix transcription factor Foxl1 is a marker for progenitor cells and their descendants in the mouse liver in vivo. Here, we purify progenitor cells from Foxl1-Cre; RosaYFP mice and evaluate their proliferative and differentiation potential in vitro. Treatment of Foxl1-Cre; RosaYFP mice w...
ORGANISM(S): Mus musculus 
2011-05-01 | E-GEOD-28890 | biostudies-arrayexpress
UnknownSpatial control of nucleoporin condensation by Fragile X-related proteins
Not available
S-SCDT-EMBOJ-2020-104467 | biostudies-other
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