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GenomicsCIITA
CIITA
PRJEB5958 | ENA
GenomicsCIITA
Creation of comprehensive CIITA and RFX5 ChIP-Seq profiles in primary B cells and monocytes
ORGANISM(S): Homo sapiens 
2014-10-08 | E-MTAB-2424 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Hodgkin lymphoma cell line KMH2: Comparison of CIITA-BX648577 knockdown cultures with non-silencing controls
Description of differentially expressed genes between KMH2 CIITA-BX648577 knockdown cultures and non-silencing controls To determine the change in gene expression after siRNA interference with the fusion transcript CIITA-BX 648577 identified in KMH2 cells.
ORGANISM(S): Homo sapiens 
2010-12-11 | E-GEOD-25987 | biostudies-arrayexpress
ProteomicsZBTB48 is a pioneer factor regulating B-cell-specific CIITA expression
CIITA is the master regulator of MHC II genes expression and hence the adaptive immune response. CIITA expression itself is tightly regulated by three cell type-specific promoters, pI, pIII, and by pIV, and can also be induced by IFNg in non-immune cells. While key regulatory elements have been iden...
ORGANISM(S): Homo sapiens (Human) 
2024-12-22 | PXD043134 | Pride
Mhc ii Adaptive immunity B cell Zinc finger Pioneer factor Molecular switch Ciita Zbtb48 
TranscriptomicsTranscription profiling of mouse dendritic cells from wild type, CIITA-/- and I-A beta -/- strains representing CIITA-deficient, MHC class II-deficient and control mice
Triplicates preparations of RNA from day 10 DC's. Experiment is described in Wong et al 2003 Nat. Immunol.
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-557 | biostudies-arrayexpress
TranscriptomicsZBTB32 Is an Early Repressor of the CIITA MHC Class II Gene Expression during B Cell Differentiation to Plasma Cells
Primary murine B cells were stimulated with IL2, IL5, LPS to induce B cell differentiation for 24 hours. RNA was extracted from control and differentiated B cell to compare gene expression. Murine B cells (CD43-) were purfied from 5 weeks old mice splenocytes. And purified B cells were stimulated wi...
ORGANISM(S): Mus musculus 
2012-07-30 | E-GEOD-17999 | biostudies-arrayexpress
ProteomicsCIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens
CD4+ T cell responses are crucial for inducing and maintaining effective anti-cancer immunity, and the identification of HLA-II cancer-specific epitopes is key to the development of potent cancer immunotherapies. In many tumor types, and especially in glioblastoma (GBM), HLA-II complexes are hardly ...
ORGANISM(S): Homo sapiens (Human) 
2021-02-03 | PXD020079 | Pride
Glioblastoma Immunopeptidomics Antigen presentation Ciita 
GenomicsOsteocyte CIITA Aggravates Osteolytic Bone Lesions in Myeloma
Osteocyte CIITA Aggravates Osteolytic Bone Lesions in Myeloma
PRJNA827810 | ENA
GenomicsRNAseq analysis of U2OS cell clones made to stably expressing exogenous CIITA
RNAseq analysis of U2OS cell clones made to stably expressing exogenous CIITA
PRJNA648965 | ENA
GenomicsCIITA regulated genes in human B cells
The MHC class II transactivator (CIITA) is essential for the expression of MHC-II genes. CIITA functions as a transcriptional activator when bound to genes although repressive roles have been reported at some loci in other cell types. To define the role of CIITA in gene regulation in human B cells, ...
ORGANISM(S): Homo sapiens 
2015-03-06 | GSE52941 | GEO
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