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ProteomicsLong-term changes following pre-conditioned circulating angiogenic cells therapy in critical limb ischemia
Critical limb ischemia (CLI), results from a severe blockade of the arterial vessels, is usually correlated to atherosclerosis. Circulating angiogenic cells (CACs) constitute a good alternative as CLI cell therapy due to their vascular regenerative potential, although the mechanisms of action of the...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD024132 | Pride
Neovascularization Circulating angiogenic cells Immune cells Atherosclerotic secretome Critical limb ischemia 
TranscriptomicsTranscription profiling of CD146 immunomagnetically enriched circulating endothelial cells (CECs) from healthy donors and patients with metastatic breast, colorectal, prostate, lung and renal cancer
Increased numbers of endothelial cells are observed in peripheral blood of cancer patients. These circulating endothelial cells (CECs) may contribute to the formation of blood vessels in the tumor or reflect vascular damage caused by treatment or tumor growth. Characterization of these cells may a...
ORGANISM(S): Homo sapiens 
2006-11-08 | E-MEXP-476 | biostudies-arrayexpress
ProteomicsCharacterization of the Angiogenic and Proteomic Features of Circulating Exosomes in a Canine Mandibular Model of Distraction Osteogenesis
While distraction osteogenesis (DO) can be an extremely effective approach to treating extensive bone defects, it entails a very long treatment period. The present study was designed with the goal of clarifying the mechanisms underlying the angiogenic and osteogenic activities characteristic of DO s...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2025-05-13 | PXD050531 | Pride
Characterization Circulating exosomes Proteomic Angiogenic Distraction osteogenesis 
ProteomicsIdentification of the initial molecular changes in response to Circulating Angiogenic Cells-mediated therapy in Critical Limb Ischemia
Circulating angiogenic cells (CACs) constitute promising candidates for cell therapy in critical limb ischemia (CLI) due to their assigned vascular regenerative properties. A label free MS-based quantitative approach was performed to identify protein changes related. We analyzed the initial molecula...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD017661 | Pride
Critical limb ischemia Angiogenesis Circulating endothelial cells Mouse Cell movement 
ProteomicsAtherosclerotic environment effect over CAC pre-angiogenic role
In response to vascular injury, early EPC or Circulating angiogenic cells (CAC) are thought to be recruited to the damaged areas, participating mainly in a paracrine fashion, by releasing pro-angiogenic factors, promoting the mobilization of other cell populations such as the late EPC, or endothelia...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019395 | Pride
Proteomics Angiogenesis Circulating angiogenic cells Atherosclerotic factors Paracrine role Endothelial colony forming cells Secretome 
ProteomicsThe serum of COVID-19 asymptomatic patients in circulating angiogenic cells ex-vivo
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has provoked, up to date, more than 5 million deaths worldwide. While asymptomatic individuals are responsible of many potential transmissions, the difficulty to identify and isolate them at the high peak of infection constitut...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD030860 | Pride
Covid-19 Asymptomatic Proteomics Endothelial dysfunction Circulating angiogenic cells Sars-cov-2 Endothelial progenitor cells 
TranscriptomicsInfection of Myeloid Angiogenic Cells (MACs) with Bartonella henselae (B.h.) induces a chord formation phenotype in vitro.
Myeloid Angiogenic Cells (MACs) were infected with the intracellular, bacterial pathogen Bartonella henselae (B.h.). Infected cells were seeded onto Matrigel coated plates. While uninfected cells showed no phenotypic changes and died over time, infected cells showed strong phenotypic changes and dev...
ORGANISM(S): Homo sapiens 
2015-04-23 | E-GEOD-55170 | biostudies-arrayexpress
ModelsSharan2014 - model of anti-VEGF agents to investigate circulating angiogenic factor modulation
No description
2016-04-27 | MODEL1604270003 | BioModels
UnknownSpecific recruitment of circulating angiogenic cells using biomaterials as filters.
Not available
S-EPMC5607627 | biostudies-literature
UnknownResidential Proximity to Major Roadways Is Associated With Increased Levels of AC133+ Circulating Angiogenic Cells.
Not available
S-EPMC4862408 | biostudies-literature
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