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TranscriptomicsMicroRNA profiling of brain metastasis competent cell-derived exosomes
Objective of this work was to characterize the miRNA profile of exosomes isolated from brain-homing cell lines (MDA-MB-231BR, CTC1BMSM, and 70W) with their respective parental non-brain metastatic cell lines (MDA-MB-231P, CTC1P and MeWo). Exosomes derived from the six cell lines were isolated. Brain...
ORGANISM(S): Homo sapiens 
2013-07-16 | E-GEOD-48934 | biostudies-arrayexpress
TranscriptomicsExosomes mediate protective messages during oxidative stress; role of exosomal shuttle RNA
Exosomes are small extracellular nano-vesicles of endocytic origin that mediate different signals between cells, by surface interactions and by shuttling of functional RNA from one cell to another. In this study, we show that exosomes, produced by mouse mast cells exposed to oxidative stress, change...
ORGANISM(S): Mus musculus 
2011-01-07 | E-GEOD-24886 | biostudies-arrayexpress
ProteomicsCharacterization of the Angiogenic and Proteomic Features of Circulating Exosomes in a Canine Mandibular Model of Distraction Osteogenesis
While distraction osteogenesis (DO) can be an extremely effective approach to treating extensive bone defects, it entails a very long treatment period. The present study was designed with the goal of clarifying the mechanisms underlying the angiogenic and osteogenic activities characteristic of DO s...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2025-05-13 | PXD050531 | Pride
Characterization Circulating exosomes Proteomic Angiogenic Distraction osteogenesis 
TranscriptomicsExosomes isolated from M.tb infected cells modulate macrophage response to IFN-gamma
we studied the role of exosomes isolated from M.tb infected macrophages in modulating the macrophage response to IFN-γ. Nimblegen microarray gene expression studies were used to compare the suppression of IFN-γ inducible genes by exosomes relative to the virulent strain of M.tuberculosis. Overall ou...
ORGANISM(S): Mus musculus 
2011-06-05 | E-GEOD-29731 | biostudies-arrayexpress
ProteomicsCirculating Microvesicles and Exosomes in Small Cell Lung Cancer by Quantitative Proteomics
Early detection of small cell lung cancer crucially demands highly reliable markers. Growing evidence suggests that extracellular vesicles carry tumor cell-specific cargo suitable as protein markers in cancer. Therefore, we isolated plasma-derived exosomes from newly diagnosed small cell lung cancer...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD028885 | Pride
Human Plasma Extracellular vesicles Lc-ms/ms 
ProteomicsMapping the Host Circulating Exosome Response to SARS-CoV-2
The knowledge of the host response to the novel coronavirus SARS-CoV-2 is still limited, slowing the understanding of COVID-19 pathogenesis and the development of therapeutic strategies. During the course of a viral infection, host cells release exosomes and other extracellular vesicles carrying vir...
ORGANISM(S): Homo sapiens (Human) 
2021-03-18 | PXD021144 | Pride
Sars-cov-2  plasma exosomes  host response  biomarkers 
TranscriptomicsTumor exosome integrins determine organotropic metastasis
Stephen Paget first proposed, in 1889, that organ distribution of metastases is a non-random event, yet metastatic organotropism remains one of the greatest mysteries in cancer biology. Here, we demonstrate that exosomes released by lung-, liver- and brain-tropic tumor cells fuse preferentially with...
ORGANISM(S): Homo sapiens 
2015-06-17 | E-GEOD-68919 | biostudies-arrayexpress
GenomicsSmall RNA sequencing of circulating exosomes from SD rats
Small RNA sequencing of circulating exosomes from SD rats
PRJNA1269930 | ENA
GenomicsGenomic analysis of lncRNA and mRNA profile in circulating exosomes of patients with rheumatic heart disease
Genomic analysis of lncRNA and mRNA profile in circulating exosomes of patients with rheumatic heart disease
PRJNA533620 | ENA
ProteomicsFibrinogen chain positive circulating exosomes are a colorectal cancer potential biomarker
Exosomes are small vesicles contain cellular nucleic acids, proteins, lipids and other substances secreted by living cells. The special structure of exosomes makes it possible to protect the inside contents exist in blood stably. Recent researches showed that exosomes are blame for tumor metastatic ...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD009490 | Pride
Colorectal cancer Exosome Protein mass spectrometry，biomarker 
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