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GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
TranscriptomicsSeedling transcriptomes of Arabidopsis thaliana HULK mutants
We produced RNA-seq reads from messenger RNA isolated from aerial seedling tissue for Arabidopsis thaliana mutants in the HULK gene family. The read data were generated with biological replication (two replicates). The resulting RNA-seq data provide a resource to assess the function of HULK genes in...
ORGANISM(S): Arabidopsis thaliana 
2015-01-01 | E-GEOD-54125 | biostudies-arrayexpress
TranscriptomicsProfiling of differential allelic expression in mouse placenta from reciprocal crosses
Many questions about the regulation, functional specialization, computational prediction, and evolution of genomic imprinting would be better addressed by having an exhaustive genome-wide catalog of genes that display parent-of-origin differential expression. As a first-pass scan for novel imprinte...
ORGANISM(S): Mus musculus 
2011-06-15 | E-GEOD-29690 | biostudies-arrayexpress
TranscriptomicsThe genetic architecture of the genome-wide transcriptional response to ER stress in the mouse
Endoplasmic reticulum (ER) stress occurs when misfolded proteins accumulate in the ER. The cellular response to ER stress involves complex transcriptional and translational changes, important to the survival of the cell. ER stress is a primary cause and a modifier of many human diseases. A first ste...
ORGANISM(S): Mus musculus 
2014-12-02 | E-GEOD-63756 | biostudies-arrayexpress
TranscriptomicsSex-biased expression in Drosophila willistoni
We performed mRNA sequencing of samples isolated from the heads, thoraxes, and abdomens of males and females of Drosophila willistoni to identify genes that are differentially expressed between the sexes. Comparison of expression levels in females and males
ORGANISM(S): Drosophila willistoni 
2012-04-08 | E-GEOD-31723 | biostudies-arrayexpress
TranscriptomicsAlternative Splicing in Erythropoiesis
Differentiating erythroid cells execute a unique gene expression program that insures synthesis of the appropriate proteome at each stage of maturation. Standard expression microarrays provide important insight into erythroid gene expression, but cannot detect qualitative changes in transcript struc...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-14588 | biostudies-arrayexpress
TranscriptomicsExpression data from Pseudomonas aeruginosa (wild type and lasRrhlR mutant strains) exposed to human neutrophils
In the present in vitro study, interactions between P. aeruginosa (sessile biofilms as well as planktonic cells) and PMNs were analyzed by means of DNA microarray based transcriptomics. We found that the P. aeruginosa wild type biofilms, in contrast to planktonic cultures and quorum sensing (QS) def...
ORGANISM(S): Pseudomonas aeruginosa 
2009-08-04 | E-GEOD-6769 | biostudies-arrayexpress
UnknownA sweet killer: mesoporous polysaccharide confined silver nanoparticles for antibacterial applications.
Not available
S-EPMC3189750 | biostudies-literature
TranscriptomicsTranscription profiling of the Arctic springtail Megaphorura arctica after cold or salt dehydration to study insect cyroprotective dehydration
The 13,824 cDNA microarray was constructed by printing 6912 PCR-amplified cDNA clones in duplicate. These were derived from a previous EST study (Clark et al, 2007) and comprised 3840 clones from the Library D2 (fully dehydrated animals, cooled to -14°C) and 3072 clones from the Library D1 (dehydrat...
ORGANISM(S): Megaphorura arctica 
2009-07-21 | E-MEXP-2105 | biostudies-arrayexpress
UnknownDetection of Antimicrobial Resistance Using Proteomics and the Comprehensive Antibiotic Resistance Database: A Case Study.
Not available
S-EPMC7378939 | biostudies-literature
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