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UnknownEpisignature Mapping of TRIP12 Provides Functional Insight into Clark-Baraitser Syndrome.
Not available
S-EPMC9690904 | biostudies-literature
TranscriptomicsMhyo IG Rnd vs MhRnd
Mycoplasma hyopneumoniae is the causative agent of porcine enzootic pneumonia and a major factor in the porcine respiratory disease complex. A clear understanding of the mechanisms of pathogenesis does not exist. The virulence factors of M. hyopneumoniae are largely unknown and are most probably com...
ORGANISM(S): Mycoplasma hyopneumoniae 
2010-06-30 | E-GEOD-17893 | biostudies-arrayexpress
TranscriptomicsEnvironmental heat stress in Greenland blue mussels (Mytilus edulis)
Background biology: Global warming has accelerated in recent decades, with the Arctic warming 2–3 times faster than the global average. As a result boreal species are expanding into the Arctic, at a pace reflecting environmental warming. Nevertheless, the poleward expansion of boreal marine species...
ORGANISM(S): Mytilus edulis 
2020-11-25 | E-MTAB-9786 | biostudies-arrayexpress
TranscriptomicsAnchoring ethinylestradiol induced gene expression changes with testicular morphology and reproductive function in the medaka
This study assessed the implications of a 14 day sub-chronic exposure of ethinylestradiol (EE2; 1.0 or 10.0 M-BM-5g/L EE2) on male medaka fertility, testicular histology and testicular gene expression. The findings demonstrate that a 14 day exposure to EE2 induced impaired male reproductive capacity...
ORGANISM(S): Oryzias latipes 
2013-03-06 | E-GEOD-44859 | biostudies-arrayexpress
TranscriptomicsDefinition of the Pseudomonas aeruginosa Anr and Dnr Regulons
The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and survival during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network. Both are proposed to bind to a non-distinguishable D...
ORGANISM(S): Pseudomonas aeruginosa 
2010-07-07 | E-GEOD-17179 | biostudies-arrayexpress
ProteomicsDynamic profiling of the protein life cycle in response to pathogens (protein)
Protein expression is regulated by production and degradation of mRNAs and proteins, but their specific relationships remain unknown. We combine measurements of protein production and degradation and mRNA dynamics to build a quantitative genomic model of the differential regulation of gene expressio...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-59792 | biostudies-arrayexpress
TranscriptomicsExpression profiles of primary bone marrow derived mouse macrophages M-bM-^@M-^S untreated and treated with LPS or LPS+PGE
The polarization of macrophages into an anti-inflammatory or regulatory phenotype plays an important role in resolving inflammation. PGE2 regulates macrophage polarization via a PKA dependent pathway. PKA phosphorylates SIKs, inhibiting their ability to phosphorylate CRTC3 in cells. This in turn ...
ORGANISM(S): Mus musculus 
2013-02-06 | E-GEOD-41833 | biostudies-arrayexpress
MetabolomicsOn-line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process
The real-time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on-line metabolomics for the monitoring of undiluted fermentation broth samples taken automatically from a 5 L bioreac...
2023-04-26 | MTBLS5197 | MetaboLights
ProteomicsImpact of increased core fucosylation on the exosome proteome in prostate cancer
Prostate cancer is the most commonly diagnosed oncogenic malignancy in men worldwide, resulting in almost 30,000 cancer-related deaths in the United States each year. Wider examination of aberrant glycosylation in prostate cancer has revealed increased expression of the glycotransferase involved in ...
ORGANISM(S): Homo sapiens (Human) 
2020-05-13 | PXD013340 | Pride
Human Glycosylation Cancer Exosomes Glycoproteomics Proteomic 
ProteomicsMass-spectrometry phosphoproteomics of Calu-3 cell lines infected with SARS-CoV-2, in comparison to non-infected and UV mock-treated cell lines
To identify the proteome alterations in human epithelial cells upon SARS-CoV-2 infection, we performed an in vitro experiment, where we infected lung-adenocarcinoma cultured human airway epithelial cells (Calu-3) with an isolate of the ancestral variant and alpha variant of SARS-CoV-2 in two separat...
ORGANISM(S): Homo sapiens (Human) 
2023-09-01 | PXD040982 | Pride
Covid-19 Phosphosites Ph fractionation Human Sars-cov-2 Calu-3 cell line Infection Phosphoproteomics Lc-ms/ms 
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