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UnknownQuantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis.
Not available
S-EPMC5544772 | biostudies-literature
UnknownESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3.
Not available
S-EPMC8581997 | biostudies-literature
ProteomicsA quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis.
Rhomboids are intramembrane serine proteases conserved in all kingdoms of life. They regulate epidermal growth factor receptor signalling in Drosophila by releasing signalling ligands from their transmembrane tethers. Their functions in mammals are poorly understood, in part because of the lack of e...
ORGANISM(S): Homo sapiens (Human) 
2017-08-14 | PXD006716 | Pride
Proteomics Ectodomain shedding Intramembrane protease Epithelia Rhomboid protease Substrate 
UnknownIdentification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes.
Not available
S-EPMC2890567 | biostudies-literature
ProteomicsFyn- and Abl-driven interactome and post-translational modifications of DCBLD1 and DCBLD2
Three related datasets are included, all from immunoprecipitations of FLAG-tagged DCBLD1 and DCBLD2 (human) from 293 cells. Letters at the end of file names denote regions of each gel lave from highest (“A”) to lowest (“B”-X) molecular weight. File names containing “SILAC” are part of a dataset comp...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Homo sapiens (Human) 
2020-08-07 | PXD017723 | Pride
Clcp1 Dcbld2 Esdn Dcbld1 
ProteomicsCLPC1 maintains chloroplast proteome and RNA homeostasis
In chloroplasts, homeostasis of the proteome maintained by protein synthesis, importation, and degradation is critical to the development of chloroplasts. The caseinolytic protease complex component CLPC1, a member of the HSP100 family of chaperones, not only facilitates the translocation of pre-pro...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-10-19 | PXD000869 | Pride
Clpc1 Rna Chloroplast Proteome Homeostasis 
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