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TranscriptomicsThe glomerular circadian clock temporally regulates basement membrane dynamics and glucocorticoid response. Cultured podocyte cells circadian clock
Kidney physiology has diurnal variation and abnormal circadian rhythm is associated with kidney disease. However, it is not known whether glomeruli, the filtering units in the kidney, are under circadian control. We therefore investigated core circadian clock components in cultered podocyte cells, t...
ORGANISM(S): Mus musculus 
2025-04-22 | E-MTAB-13459 | biostudies-arrayexpress
ProteomicsPost-transcriptional glucocorticoid receptor signalling synchronises circadian rhythms
Circadian rhythms are driven by cellular clocks throughout the body that maintain optimal health. Glucocorticoid (GC) hormones are vital for synchronising cellular clocks, aligning them with external day/night cycles, but mechanistic understanding is incomplete. We use a glucocorticoid receptor KO/r...
ORGANISM(S): Homo sapiens (Human) 
2026-09-04 | PXD081613 | Pride
Nuclear hormone receptor Rna processing Circadian rhythm Glucocorticoid Clock synchronisation Entrainment Post-transcriptional regulation 
TranscriptomicsLight can synchronise peripheral clocks autonomously from each other
Organisms have adapted to the changing environmental conditions within the 24h cycle of the day by temporally segregating tissue physiology to the optimal time of the day. On the cellular level temporal segregation of physiological processes is established by the circadian clock, a Bmal1 dependent t...
ORGANISM(S): Mus musculus 
2019-03-25 | GSE115104 | GEO
TranscriptomicsLight can synchronise peripheral clocks autonomously from each other [darkness experiment (DD)]
Organisms have adapted to the changing environmental conditions within the 24h cycle of the day by temporally segregating tissue physiology to the optimal time of the day. On the cellular level temporal segregation of physiological processes is established by the circadian clock, a Bmal1 dependent t...
ORGANISM(S): Mus musculus 
2019-03-25 | GSE114943 | GEO
ProteomicsCircadian Regulation of Protein Cargo in Exosomes
The circadian clock controls many aspects of physiology, but it remains undescribed whether extracellular vesicles (including exosomes) involved in cell-cell communications between tissues are regulated in a circadian pattern. We demonstrate a 24 h rhythmic abundance of individual proteins in exosom...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-19 | PXD022393 | Pride
Exosomes Lc-ms Circadian rhythm 
UnknownComparing Circadian Dynamics in Primary Derived Stem Cells from Different Sources of Human Adult Tissue.
Not available
S-EPMC5672638 | biostudies-literature
UnknownMisalignment with the external light environment drives metabolic and cardiac dysfunction.
Not available
S-EPMC5595905 | biostudies-literature
UnknownA spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamics.
Not available
S-EPMC3046134 | biostudies-literature
GenomicsLight can synchronise peripheral clocks autonomously from each other
Light can synchronise peripheral clocks autonomously from each other
PRJNA473798 | ENA
GenomicsLight can synchronise peripheral clocks autonomously from each other [darkness experiment (DD)]
Light can synchronise peripheral clocks autonomously from each other [darkness experiment (DD)]
PRJNA473160 | ENA
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