iTRAQ quantitative proteome of wild and CMTM4 knockout mouse testis tissue.Integrative analysis of phenotype and testicular quantitative proteome of CKLF-like MARVEL transmembrane domain-containing protein 4 (CMTM4) deficiency mouse reveal its association with male fertility.
Cmtm4 Knockout mouse was constructed by CRISPR-Cas9 technology, and the KO mice showed male infertility. A proteomic anlaysis of sperm proteins was performed by comparing KO and WT mice.
