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ProteomicsSperm proteome of CMTM4-deficient mice
Cmtm4 Knockout mouse was constructed by CRISPR-Cas9 technology, and the KO mice showed male infertility. A proteomic anlaysis of sperm proteins was performed by comparing KO and WT mice.
ORGANISM(S): Mus musculus (Mouse) 
2019-05-21 | PXD013092 | Pride
Sperm Knockout Proteome Cmtm4 
ProteomicsIntegrative analysis of phenotype and testicular quantitative proteome of CKLF-like MARVEL transmembrane domain-containing protein 4 (CMTM4) deficiency mouse reveal its association with male fertility
iTRAQ quantitative proteome of wild and CMTM4 knockout mouse testis tissue.Integrative analysis of phenotype and testicular quantitative proteome of CKLF-like MARVEL transmembrane domain-containing protein 4 (CMTM4) deficiency mouse reveal its association with male fertility.
ORGANISM(S): Mus musculus (Mouse) 
2019-03-18 | PXD011936 | Pride
Cmtm4 itraq 
GenomicsThe role of CMTM4 in hepatocellular carcinoma
The role of CMTM4 in hepatocellular carcinoma
PRJNA776163 | ENA
GenomicsModulation of tumor drug sensitivity and inflammatory signaling through CMTM4
Modulation of tumor drug sensitivity and inflammatory signaling through CMTM4
PRJNA1179308 | ENA
ProteomicsCMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology
Interleukin-17A (IL-17A) is a key mediator of protective immunity to yeast and bacterial infections but also drives the pathogenesis of several autoimmune diseases, such as psoriasis or psoriatic arthritis. Here, we show that the tetra-transmembrane protein CMTM4 is a subunit of the IL-17 receptor (...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-02 | PXD036366 | Pride
Cmtm4 Il-17 receptor signaling complex Il-17a Il-17rc 
TranscriptomicsThe role of CMTM4 in hepatocellular carcinoma
Dysregulation of CMTM4 has been observed in serveral cancers. Recent studies have showed that CMTM4 plays a key role in immune checkpoint therapy in tumors. To obtain a detailed view of genes and related pathways regulated by CMTM4 in the liver cancer, we used RNA-seq in liver Hep 3B cells with CMTM...
ORGANISM(S): Homo sapiens 
2024-10-28 | GSE186815 | GEO
TranscriptomicsModulation of tumor drug sensitivity and inflammatory signaling through CMTM4
Although the association between inflammation and cancer development has been recognized, how inflammation affects the outcomes of immunotherapy and chemotherapy hasn’t yet been well evaluated. In this study, we found that CKLF-like MARVEL transmembrane domain-containing member 4 (CMTM4) was highly ...
ORGANISM(S): Mus musculus 
2024-11-07 | GSE280512 | GEO
UnknownCMTM4 inhibits gastric tumorigenesis and metastasis.
Not available
S-EPMC11399846 | biostudies-literature
UnknownMARVEL domain containing CMTM4 affects CXCR4 trafficking.
Not available
S-EPMC9634968 | biostudies-literature
UnknownModulation of tumor inflammatory signaling and drug sensitivity by CMTM4.
Not available
S-EPMC11914105 | biostudies-literature
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