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MetabolomicsM-CMV infected Nicotiana tabacum
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ORGANISM(S): Nicotiana tabacum 
ST000497 | MetabolomicsWorkbench
TranscriptomicsSmall RNAs from Arabidopsis plants infected with CMV-?2b
We focused our analyses on the description of viral (CMV-?2b) and, based on genetic and molecular evidence, classified them and discussed their relevance in antiviral defense. Small RNAs from Arabidopsis plants from different genetic backgrounds infected with (CMV-?2b) were sequenced before or after...
ORGANISM(S): Arabidopsis thaliana 
2012-03-01 | E-GEOD-27477 | biostudies-arrayexpress
TranscriptomicsIdentification of MicroRNAs and Their Targets in Tomato Infected with Cucumber Mosaic Virus
We constructed two independent small RNA libraries from leaves of mock and Cucumber mosaic virus (CMV) infected tomatoes, respectively, and sequenced with a high-throughput Illumina Solexa system. Based on sequence analysis and hairpin structure prediction, a total of 50 known miRNAs (32 families) a...
ORGANISM(S): Solanum lycopersicum 
2014-10-20 | E-GEOD-56974 | biostudies-arrayexpress
TranscriptomicsDistinct gene expression profiles associated with the susceptibility of pathogen-specific CD4 T cells to HIV-1 infection
Analysis of global gene expression profiles of flow cytometry-sorted, different pathogen-specific CD4+ T cell populations from the same peripheral blood mononuclear cells (PBMC), to identify molecular parameters that regulate differential susceptibilities of these CD4+ T cells to HIV infection. The ...
ORGANISM(S): Homo sapiens 
2012-12-13 | E-GEOD-42853 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fetal gammadelta T cells from that cytomegalovirus (CMV) positive or negative
Response of fetal gammadelta T cells towards infection with human cytomegalovirus (CMV)
ORGANISM(S): Homo sapiens 
2009-12-12 | E-MEXP-2055 | biostudies-arrayexpress
TranscriptomicsCMV 2b immunoprecipitated small RNAs data set
We report that CMV2b exist in a complex of sRNAs in arabidopsis, with significant preference to repeat-associated AGO4-related 24nt siRNAs. This differential selection of siRNAs in vivo helps CMV 2b to perturb host epigenetic defense in the form of transposons activation and severeal repeat associat...
ORGANISM(S): Arabidopsis thaliana 
2013-01-18 | E-GEOD-23771 | biostudies-arrayexpress
TranscriptomicsDigital gene expression (DGE) of CMV-infected tobacco leaves
Here we performed a transcriptomic study on complete symptom development process of CMV-infected Nicotiana tabacum using Solexa/Illumina's high-throughput digital gene expression (DGE) system. 12 DGE libraries (from six virus-infected samples and six corresponding mock-inoculated samples) were const...
ORGANISM(S): Nicotiana tabacum 
2012-11-09 | E-GEOD-30162 | biostudies-arrayexpress
TranscriptomicsCMV-Specific CD8+ Memory T Cells Re-Emerge After Viral Challenge And Recapitulate CMV Immunity Under Various Adoptive Transfer Conditions
Reconstitution of cytomegalovirus (CMV)-specific immunity following transplant remains a primary clinical objective to prevent CMV disease, and adoptive immunotherapy of CMV-specific T cells can be an effective therapeutic approach. Due to the persistence of CMV, most CMV-specific CD8+ T cells becom...
ORGANISM(S): Mus musculus 
2015-01-28 | E-GEOD-61927 | biostudies-arrayexpress
TranscriptomicsCMV infection induces a rapid and sustained change in the expression of Natural Killer Cell Receptors on CD8+ T Cells
The CD8+ T cell compartment of human cytomegalovirus (CMV) seropositive individuals characteristically contains a high proportion of cells that expresses Natural Killer Cell Receptors (NKR) which may contribute to the surveillance of virus-infected cells. To test if this enhanced expression is a dir...
ORGANISM(S): Homo sapiens 
2008-08-28 | E-GEOD-12589 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile of CMV-specific CD4+ T cells and CD4+CCR7-CD45RA- T cells (effector memory T cells of CMV-seronegative
Infection with cytomegalovirus is characterised by very strong and sustained T cell responses in peripheral blood. These expansions increase even further with age and research suggests CMV-specific T cells may contribute towards development of accelerated immune senescence and vascular disease in el...
ORGANISM(S): Homo sapiens 
2016-08-07 | E-MTAB-4510 | biostudies-arrayexpress
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