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ProteomicsEvaluation of antifungal activity of Naja pallida and Naja mossambica venoms against three Candida species
In contrast to comprehensively investigated antibacterial activity of snake venoms, namely crude venoms and their selected components, little is known about antifungal properties of elapid snake venoms. In the present study, the proteome of two venoms of red spitting cobra Naja pallida (NPV) and Moz...
ORGANISM(S): Naja mossambica Naja pallida 
2020-08-12 | PXD020450 | Pride
Naja pallida Naja mossambica Cobra venoms Candida albicans 
ProteomicsProteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications and Presence of Extracellular Vesicles
Latest advancement of omics technologies allows in-depth characterization of venom compositions. In the present work we present a proteomic study of two snake venoms of the genus Naja i.e. Naja naja (black cobra) and Naja oxiana (brown cobra), of Pakistani origin. The present study has shown that th...
ORGANISM(S): Naja naja Naja oxiana 
2020-10-29 | PXD018726 | Pride
Naja naja  naja oxiana  venom proteome 
ProteomicsDenaturing and native top-down venomics: Mapping proteoforms and protein complexes from king cobra venom
Characterizing whole proteins by top-down proteomics avoids a step of inference encountered in the dominant bottom-up methodology when peptides are assembled computationally into proteins for identification. The direct interrogation of whole proteins and protein complexes from the venom of Ophiophag...
ORGANISM(S): Ophiophagus hannah (King cobra) (Naja hannah) 
2016-05-18 | PXD003403 | Pride
King cobra venom Top-down proteomics Proteoforms Native mass spectrometry Protein complexes 
MetabolomicsOrganic and Peptidyl Constituents of Snake Venoms: The Picture Is Vastly More Complex Than We Imagined
Small metabolites and peptides in 17 snake venoms (Elapidae, Viperinae, and Crotalinae), were quantified using liquid chromatography-mass spectrometry. Each venom contains >900 metabolites and peptides. Many small organic compounds are present at levels that are probably significant in prey envenoma...
2023-01-11 | MTBLS755 | MetaboLights
ProteomicsGenus wide venom proteomics of cobras (Naja)
Genus-wide proteomics analysis of cobra (Naja) venoms. For top-down analysis, venom samples were reduced with TCEP and measured via HPLC-MS/MS (Q-Exactive) . Spectrum-Protein matching was performed with TopPic1.1 against a genus wide translated transcriptome database and NCBI protein entries from th...
ORGANISM(S): Naja (ncbitaxon:8638) 
2018-01-04 | MSV000081885 | MassIVE
UnknownDevelopment of a Broad-Spectrum Antiserum against Cobra Venoms Using Recombinant Three-Finger Toxins.
Not available
S-EPMC8402450 | biostudies-literature
UnknownDifferential effects of the venoms of Russell's viper and Indian cobra on human myoblasts.
Not available
S-EPMC10850160 | biostudies-literature
UnknownThe Proteome of African Spitting and Non-Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells.
Not available
S-EPMC12371851 | biostudies-literature
OtherMolecular dissection of cobra venom highlights heparinoids as an effective snakebite antidote
Snakebite affects ~1.8 million people annually. The current standard of care are antibody-based antivenoms, which are difficult to access and are not effective against local tissue injury, the primary cause of morbidity. Here we use a functional genomics approach to define human genes that genetical...
ORGANISM(S): Homo sapiens 
2025-04-06 | GSE262798 | GEO
GenomicsMolecular dissection of cobra venom highlights heparinoids as an effective snakebite antidote
Molecular dissection of cobra venom highlights heparinoids as an effective snakebite antidote
PRJNA1093400 | ENA
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