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ProteomicsNemo-like kinase drives Foxp3 stability and is critical for maintenance of immune tolerance by regulatory T cells
The Foxp3 transcription factor is a crucial determinant of both regulatory T (TREG) cell development and their functional maintenance. Appropriate modulation of tolerogenic immune responses therefore requires tight regulation of Foxp3 transcriptional output, and this involves both transcriptional an...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-02 | PXD011164 | Pride
Nlk Ubiquitination Phosphorylation Foxp3 Nlk Tcr Immune tolerance Regulatory t cell 
TranscriptomicsRNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients
Through RNA sequencing of CD4+ Tmemory/effector cells derived from the synovium of JIA patients and healthy controls, we analyzed the JIA gene expression signature. Treatment of autoinflammatory site-derived patient T cells with the BET-inhibitor JQ1 inhibited immune-related super-enhancers and pref...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-71595 | biostudies-arrayexpress
UnknownTemporal Stability of Seagrass Extent, Leaf Area, and Carbon Storage in St. Joseph Bay, Florida: a Semi-automated Remote Sensing Analysis.
Not available
S-EPMC10054859 | biostudies-literature
UnknownFoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1.
Not available
S-EPMC2172323 | biostudies-literature
UnknownMetabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.
Not available
S-EPMC3869884 | biostudies-literature
TranscriptomicsHDAC inhibition by TSA and Butyrate In Flt3L-elicited DC
Butyrate induces Treg via HDACi activity Microarray of DC treated with TSA or Butyrate over untreated
ORGANISM(S): Mus musculus 
2013-10-15 | E-GEOD-51263 | biostudies-arrayexpress
UnknownNemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells.
Not available
S-EPMC6444001 | biostudies-literature
UnknownProviding a framework for seagrass mapping in United States coastal ecosystems using high spatial resolution satellite imagery.
Not available
S-EPMC10622156 | biostudies-literature
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