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TranscriptomicsGenome plasticity in Streptomyces: identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-26 | E-GEOD-2994 | biostudies-arrayexpress
TranscriptomicsRegional organization of gene expression in Streptomyces coelicolor
Based on the chromosomal locations of genes inferred from sequence analysis to be essential for the viability of Streptomyces coelicolor, Bentley et al. (Bentley et al., 2002) have suggested that a 4.9 Mb central region of the linear S. coelicolor chromosome encodes core functions expressed during v...
ORGANISM(S): Streptomyces coelicolor 
2005-07-12 | E-GEOD-2921 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human mammary epithelial cells HMECs (S-FL, S-P and PGA) during replicative senescence
Telomere shortening in populations of human mammary epithelial cells (HMECs) that survive early replicative arrest (M0) by the inactivation of p16INK4A during cell culture on plastic dishes leads to a state of permanent replicative arrest termed senescence. While culture of HMECs on feeder layers ab...
ORGANISM(S): Homo sapiens 
2005-11-01 | E-SMDB-2046 | biostudies-arrayexpress
UnknownPhase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer.
Not available
S-EPMC8259133 | biostudies-literature
TranscriptomicsComparative genomic hybridization Streptomyces coelicolor A3(2) strains
The chromosomes of several widely used laboratory derivatives of Streptomyces coelicolor A3(2) were found to have 1.06 Mb inverted repeat sequences at their termini (i.e. long-terminal inverted repeats; L-TIRs), which are 50 times the length of the 22 kb TIRs of the sequenced S. coelicolor strain M1...
ORGANISM(S): Streptomyces coelicolor 
2005-07-21 | E-SMDB-2740 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Streptomyces coelicolor
Based on the chromosomal locations of genes inferred from sequence analysis to be essential for the viability of Streptomyces coelicolor, Bentley et al. (Bentley et al., 2002) have suggested that a 4.9 Mb central region of the linear S. coelicolor chromosome encodes core functions expressed during v...
ORGANISM(S): Streptomyces coelicolor 
2005-06-20 | E-SMDB-3219 | biostudies-arrayexpress
TranscriptomicsComparative Transcript Abundance in E. Coli Degradosome Mutants and their Parental Strains
Comparative transcript abundance in E. Coli degradosome mutants and their parental strains. Abstract: RNase E, an essential endoribonuclease of Escherichia coli, interacts through its C-terminal region with multiple other proteins to form a complex termed the RNA degradosome. To investigate the degr...
ORGANISM(S): Escherichia coli 
2006-01-05 | E-GEOD-3977 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Streptomyces coelicolort time series
A complex programme of regulation governs gene expression during development of the morphologically and biochemically complex eubacterial genus Streptomyces. Earlier work has suggested a model in which 'higher level' pleiotropic regulators activate 'pathway-specific' regulators located within chromo...
ORGANISM(S): Streptomyces coelicolor 
2005-12-02 | E-SMDB-3554 | biostudies-arrayexpress
TranscriptomicsCross-regulation among disparate antibiotic biosynthetic pathways of Streptomyces coelicolor
A complex programme of regulation governs gene expression during development of the morphologically and biochemically complex eubacterial genus Streptomyces. Earlier work has suggested a model in which 'higher level' pleiotropic regulators activate 'pathway-specific' regulators located within chromo...
ORGANISM(S): Streptomyces coelicolor 
2006-02-01 | E-GEOD-4138 | biostudies-arrayexpress
UnknownCitizens' reactions to global crises: a longitudinal study during the COVID-19 pandemic in Israel.
Not available
S-EPMC9843104 | biostudies-literature
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