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MetabolomicsCold exposure aggravates vein occlusion through non-shivering thermogenesis-induced thrombocytopoiesis
Vein occlusion (VO), including deep venous thrombosis (DVT) and retinal vein occlusion (RVO), is a common cause of multiple diseases that severely compromise the quality of life of affected individuals. Epidemiological evidence indicates that VO prevalence increases in cold seasons, yet the underlyi...
2026-07-08 | MTBLS14667 | MetaboLights
MetabolomicsMild cold exposure mitigates ischemic heart injury through indole-3-acetamide–AHR-mediated SMAD2 proteolysis

Ambient temperature profoundly influences organismal metabolism, physiology, and disease. While cold exposure is a well-recognized risk factor for the onset of myocardial infarction (MI), its impact on the injured heart after MI remains unexplored. Here,&nb...

2026-03-03 | MTBLS13965 | MetaboLights
MetabolomicsBrown-fat-mediated tumour suppression by cold-altered global metabolism

Glucose uptake is essential for cancer glycolysis and is involved in non-shivering thermogenesis of adipose tissues. Most cancers use glycolysis to harness energy for their infinite growth, invasion and metastasis. Activation of thermogenic metabolism in brown adipose tissue (BAT) by cold an...

2022-08-12 | MTBLS4856 | MetaboLights
MetabolomicsEffects of cold exposure on serum lipidomic in mice
Not available
ORGANISM(S): Mus musculus 
ST001206 | MetabolomicsWorkbench
MetabolomicsTranscriptomic and metabolomic comparison of two Kandelia obovata cultivas in response to cold wave
Temperature is the primary environmental factor that restricts the growth and distribution of mangrove plants. With the escalating severity of global climate change, Kandelia obovata has gained widespread recognition as an ideal species for investigating the response mechanisms of mangroves to cold ...
2024-09-27 | MTBLS9845 | MetaboLights
MetabolomicsMouse Brown Adipose Tissue Lipidomics under Cold and Dietary Fat Interventions
This study investigates lipidomic remodeling in mouse brown adipose tissue under a 2 × 3 experimental design involving environmental condition and dietary fatty acid composition. Mice were maintained at room temperature with ad libitum feeding or exposed to 4°C cold conditions with 70% calorie restr...
2026-06-01 | MTBLS14642 | MetaboLights
MetabolomicsABA accumulation confers cross-adaptation to saline-alkali and cold stresses in alfalfa

Combined saline-alkali and cold stresses severely constrain plant growth at middle and high latitudes. Plants have evolved cross-adaptation mechanisms wherein exposure to one stress enhances resistance to another. However, the specific mechanisms driving cross-adaptation between saline-alkali and...

2026-03-22 | MTBLS14108 | MetaboLights
MetabolomicsMetabolomic profiling of goat testicular tissue under graded uranium exposure

This study presents metabolomic profiles of goat testicular tissue obtained under controlled exposure conditions. An untargeted metabolomics approach was applied to characterize global metabolic alterations associated with environmental contaminants. The dataset provides information on small-mole...

2026-03-23 | MTBLS14119 | MetaboLights
MetabolomicsThe effects of a training program encompassing cold exposure, breathing exercises, and meditation on plasma metabomics during experimental human endotoxemia
Not available
ORGANISM(S): Homo sapiens 
ST001251 | MetabolomicsWorkbench
TranscriptomicsGene expression of Drosophila melanogaster in response to multiple cold exposures
In the field, insects suffer multiple cold exposures during winter. When exposed to repeated low temperatures, Drosophila melanogaster females showed an increase in survival, but a reduction in reproduction. In this study, the microarrays were used to analyze the gene expression of female D. melanog...
ORGANISM(S): Drosophila melanogaster 
2011-09-01 | E-MEXP-3194 | biostudies-arrayexpress
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