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TranscriptomicsTranscription profiling of human fibroblasts grown on TCPS plates, Collagen-GAG 2 D plate and Collagen-GAG 3D mesh
All mRNA was isolated after 8 hours of culture time in each of three culture conditions. (1) TCPS Plate, (2) Collagen-GAG 2 dimensional coated plate and (3) collagen-GAG three dimensional mesh.
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1937 | biostudies-arrayexpress
MetabolomicsSex-dependent metabolic remodeling of kidneys revealed by arteriovenous metabolomics

Sex is a fundamental biological variable important in biomedical research, drug development, clinical trials, and prevention approaches. Among many organs, kidneys are known to exhibit remarkable structural, histological, and pathological differences between sexes. However, whether and how kidney...

2026-03-04 | MTBLS13977 | MetaboLights
ProteomicsA Macrophage-Collagen Fragment Axis Mediates Subcutaneous Adipose Tissue Remodeling
Efficient collagen degradation is essential for adaptive subcutaneous adipose tissue (SAT) expansion that protects against ectopic lipid deposition during weight gain. Here, we aimed to further define the mechanism for this collagenolytic process. We show that loss of collagen type-1 (CT1) and incre...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-16 | PXD043721 | Pride
Collagen fragments Macrophages Fibrosis Ecm-remodeling Collagen endocytosis Subcutaneous adipose tissue Cd206 
TranscriptomicsTranscription profiling time series of the growth of human IMR-90 cells seeded on a collagen/chondroitin sulfate tissue engineering scaffold
A series of chips with some repeated measurments. Each chip represents a pool of 4 collagen/chondroitin sulfate tissue engineering scaffold meshes seeded with 1 x 10^6 IMR-90 Human Fibroblasts. mRNA was isolated at 30 minutes, 1, 2, 4, 8, 12, 24, 48, and 72 hours after seeding.
ORGANISM(S): Homo sapiens 
2007-12-13 | E-GEOD-409 | biostudies-arrayexpress
ProteomicsProteomic and degradomic signatures of extracellular matrix remodeling in calcific aortic valve
Calcific aortic valve disease (CAVD) is the most common valvular heart disease in older adults, but no medical therapy is currently able to halt or reverse its progression, partly because the molecular mechanisms of valve remodeling remain incompletely understood. Here, we aimed to dissect the extra...
ORGANISM(S): Homo sapiens (Human) 
2026-05-29 | PXD073246 | Pride
Aortic valve stenosis Extracellular matrix remodeling proteomics Calcific aortic valve disease Collagen post-translational modifications 
GenomicsNeurotropic virus-induced astrocyte remodeling links collagen-rich extracellular matrix to the LINC00460–miR-4443 regulatory axis
Neurotropic virus-induced astrocyte remodeling links collagen-rich extracellular matrix to the LINC00460–miR-4443 regulatory axis
PRJNA1521247 | ENA
GenomicsMmp14-Dependent Remodeling of the Pericellular-Dermal Collagen Interface Governs Fibroblast Survival
Mmp14-Dependent Remodeling of the Pericellular-Dermal Collagen Interface Governs Fibroblast Survival
PRJNA1108711 | ENA
ProteomicsTumor microenvironment remodeling by cancer cell-released tracks on type I collagen
Metastasis is the leading cause of cancer-related deaths. During this process, tumor cells acquire invasive and migratory capacities in order to invade the surrounding tissues. To achieve this, the tumor microenvironment is altered to facilitate cancer cells proliferation and dissemination. Multiple...
ORGANISM(S): Homo sapiens (Human) 
2026-02-24 | PXD035152 | Pride
Extracellular vesicles Type i collagen fibers Migration 
GenomicsNeurotropic virus-induced astrocyte remodeling links collagen-rich extracellular matrix to the LINC00460–miR-4443 regulatory axis [nCounter Flex]
Neurotropic virus-induced astrocyte remodeling links collagen-rich extracellular matrix to the LINC00460–miR-4443 regulatory axis [nCounter Flex]
PRJNA1526780 | ENA
UnknownCollagen turnover during cervical remodeling involves both intracellular and extracellular collagen degradation pathways†.
Not available
S-EPMC11996760 | biostudies-literature
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