Sort   by:  
 Page size 
TranscriptomicsMutation of the RNA polymerase M-NM-2-subunit gene promotes hetero-to-homo conversion of M-CM-^_-lactam resistance of methicillin-resistant Staphylococcus aureus
Three types of phenotypic expression of M-CM-^_-lactam resistance has been reported in MRSA: heterogeneous-, homogeneous-, and Eagle-type resistance. Heterogeneous to homogeneous (hetero-to-homo) conversion of M-CM-^_-lactam resistance is postulated to be caused by a chromosomal mutation (chr*) toge...
ORGANISM(S): Staphylococcus aureus 
2013-08-27 | E-GEOD-42218 | biostudies-arrayexpress
TranscriptomicsGenome-wide prediction and validation of M-OM-^C70 promoters in Lactobacillus plantarum WCFS1
Background: In prokaryotes, sigma factors are essential for the targeting of the transcription machinery to promoters. Various sigma factors have been described that recognize and bind to specific DNA sequence motifs in promoter sequences. The canonical sigma factor M-OM-^C70 is commonly involved in...
ORGANISM(S): Lactobacillus plantarum WCFS1 
2012-03-28 | E-GEOD-36898 | biostudies-arrayexpress
MetabolomicsTwo Poplar-Associated Bacterial Isolates Induce Additive Favorable Responses in a Constructed Plant-Microbiome System
The biological function of the plant-microbiome system is the result of contributions from the host plant and microbiome members. The Populus root microbiome is a diverse community that has high abundance of β- and γ-Proteobacteria, both classes which include multiple plant-growth promoting represen...
2017-07-25 | MTBLS332 | MetaboLights
TranscriptomicsA Single Amino-Acid Substitution of RNA Polymerase M-CM-^_ subunit Confers A Novel Class of VISA phenotype on hVISA Strain Mu3
hVISA clinical strain Mu3 spontaneously generates VISA at an extremely high frequency (1x10-6 or greater) within its cell population. The VISA-converted mutant strains generally grow slower than their parent hVISA strain, but they usually form colonies on vancomycin-containing agar plates after 48 h...
ORGANISM(S): Staphylococcus aureus 
2014-03-31 | E-GEOD-50826 | biostudies-arrayexpress
UnknownHuman iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation.
Not available
S-EPMC5615077 | biostudies-literature
UnknownDecrypting the programming of β-methylation in virginiamycin M biosynthesis.
Not available
S-EPMC10006238 | biostudies-literature
TranscriptomicsPeripheral tissue instruction is the primary determinant of CD8+ T cell pathogenicity: transcription profiling by array of donor CD8+ effector T cells isolated from the secondary lymphoid organs, blood and GVHD-target organs at D+6 post-transplant (F>M model)
This study reports the evolution of the donor CD8 effector T cell transcriptomes at multiple sites and time points within the same host following allo-SCT. Donor derived CD8+ T cells were flow sorted from multiple organs in mice developing GVHD in two clinically relevant murine models of H-2b MHC-ma...
ORGANISM(S): Mus musculus 
2018-03-28 | E-MTAB-5379 | biostudies-arrayexpress
TranscriptomicsFed L1 larvae total RNA levels by microarray
Here we exploit the essential process of XM-bM-^@M-^Pchromosome dosage compensation to elucidate basic mechanisms that control the assembly, genomeM-bM-^@M-^Pwide binding, and function of gene regulatory complexes that act over large chromosomal territories. We demonstrate that a subunit of C. ele...
ORGANISM(S): Caenorhabditis elegans 
2011-03-01 | E-GEOD-25831 | biostudies-arrayexpress
TranscriptomicsA mutation of RNA polymerase β’ subunit (RpoC) converts heterogeneously vancomycin-intermediate S. aureus (hVISA) into ‘slow-VISA’ (sVISA)
Various mutations in the rpoB gene, which encodes the RNA polymerase beta subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate S. aureus (VISA) and hetero-VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently ...
ORGANISM(S): Staphylococcus aureus 
2015-05-08 | E-GEOD-65338 | biostudies-arrayexpress
UnknownPharmacological Treatments of Temporomandibular Disorders: A Systematic Review Including a Network Meta-Analysis.
Not available
S-EPMC10789663 | biostudies-literature
Sort   by:  
 Page size