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MetabolomicsCharacteristics of myocardial structure and central carbon metabolism during the early and compensatory stages of cardiac hypertrophy
Cardiac hypertrophy is a classical forerunner of heart failure and myocardial structural and metabolic remodeling are closely associated with cardiac hypertrophy. We aim to investigate the characteristics of myocardial structure and central carbon metabolism of cardiac hypertrophy at different stage...
2024-08-23 | MTBLS10555 | MetaboLights
MetabolomicsEnterohepatic Axis Reprogramming via S1PR2 Inhibition Activates Compensatory Microbiota-Bile Acid Crosstalk to Ameliorate Colitis

Studies have revealed that gut microbiota dysbiosis and bile acid metabolism play pivotal roles in the pathogenesis of inflammatory bowel disease, and there exists a reciprocal interaction between gut microbiota and bile acid metabolism. S1PR2, a G protein-coupled receptor, has been demonstrated...

2025-12-19 | MTBLS13508 | MetaboLights
ProteomicsEarly cell specific transcriptional changes during compensatory renal hypertrophy
The mechanism driving the remarkable ability of the remaining kidney to enlarge and increase its function following the removal of its contralateral pair remains elusive. To explore the pathways driving compensatory renal hypertrophy, comprehensive RNA-seq transcriptional studies were undertaken in ...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-19 | PXD047516 | Pride
Hypertrophy Growth Compensatory Cholesterol Nephrectomy 
TranscriptomicsBP001-002: The genomic landscape of compensatory evolution
Adaptive evolution is generally assumed to progress through the accumulation of beneficial mutations. However, deleterious mutations may also have an important role by promoting adaptive genetic changes that are otherwise inaccessible. Here we study the capacity of the bakerM-bM-^@M-^Ys yeast genome...
ORGANISM(S): Saccharomyces cerevisiae BY4741 
2014-08-27 | E-GEOD-55373 | biostudies-arrayexpress
ProteomicsProteomic assessments of muscle tissues in cattle that are diet restricted and subsequently undergo compensatory growth
Compensatory growth is a naturally occurring accelerated growth phenomenon observed in cattle upon re-alimentation following a prior period of dietary restriction (Hornick et al., 2000). It is incorporated into man production systems as a method to reduce feed costs and consequently is economically ...
ORGANISM(S): Bos taurus (Bovine) 
2020-02-17 | PXD014374 | Pride
Bovine Compensatory growth Lc/ms-ms 
ProteomicsEarly Signaling Events in Renal Compensatory Hypertrophy Revealed by Multi-Omics
Loss of a kidney results in compensatory growth of the remaining kidney, a phenomenon of considerable clinical importance. However, the mechanisms involved are largely unknown. Here, we used a multi-omic approach in a mouse unilateral nephrectomy model to identify signaling processes associated with...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-05 | PXD036395 | Pride
Transcriptome Pparα Proximal tubule Unilateral nephrectomy Proteome Hypertrophy 
ProteomicsSignaling in Renal Compensatory Hypertrophy Revealed by Multi-Omics_Outer Cortex
This mouse kidney outer cortex proteomics data set is part of multi-omic approach in a mouse unilateral nephrectomy model to identify signaling processes associated with compensatory hypertrophy of the renal proximal tubule.
ORGANISM(S): Mus musculus (Mouse) 
2023-06-05 | PXD039697 | Pride
Unilateral nephrectomy Multi-omics Hypertrophy Proteomics Kidney 
TranscriptomicsBP001-002-pub:The genomic landscape of compensatory evolution
This hybset contains the expression profiles of several yeast deletion mutants, grown after normal and evolution conditions
ORGANISM(S): Saccharomyces cerevisiae 
2014-07-01 | E-MTAB-2352 | biostudies-arrayexpress
GenomicsAn aging-sensitive compensatory neuroprotective factor that confers cognitive resilience
An aging-sensitive compensatory neuroprotective factor that confers cognitive resilience
PRJNA1089560 | ENA
TranscriptomicsExpression data for plant compensatory responses
Plant compensatory responses depends on transcriptional reprogramming. We used microarray analysis to understand the differential gene expression pattern between clipped (herbivore browsed) and unclipped plant. Arabidopsis ecotypes Columbia and Landsberg erecta were chosen due to their differential ...
ORGANISM(S): Arabidopsis thaliana 
2013-03-02 | E-GEOD-44781 | biostudies-arrayexpress
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